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Ex vivo drug sensitivity screening predicts response to temozolomide in glioblastoma patients and identifies candidate biomarkers.
Ntafoulis I, Kleijn A, Ju J, Jimenez-Cowell K, Fabro F, Klein M, Chi Yen RT, Balvers RK, Li Y, Stubbs AP, Kers TV, Kros JM, Lawler SE, Beerepoot LV, Kremer A, Idbaih A, Verreault M, Byrne AT, O'Farrell AC, Connor K, Biswas A, Salvucci M, Prehn JHM, Lambrechts D, Dilcan G, Lodi F, Arijs I, van den Bent MJ, Dirven CMF, Leenstra S; GLIOTRAIN consortium; Lamfers MLM. Ntafoulis I, et al. Among authors: lawler se. Br J Cancer. 2023 Oct;129(8):1327-1338. doi: 10.1038/s41416-023-02402-y. Epub 2023 Aug 24. Br J Cancer. 2023. PMID: 37620410 Free PMC article.
Intracranial CAR-T cell delivery in glioblastoma patients.
Vaughn-Beaucaire P, Choi MJ, Liang O, Lawler SE. Vaughn-Beaucaire P, et al. Among authors: lawler se. Trends Cancer. 2024 Jun;10(6):478-480. doi: 10.1016/j.trecan.2024.05.002. Epub 2024 May 22. Trends Cancer. 2024. PMID: 38777680
Cancer immune profiling unveils biomarkers, immunological pathways, and cell type score associated with glioblastoma patients' survival.
Moreno DA, da Silva LS, Gomes I, Leal LF, Berardinelli GN, Gonçalves GM, Pereira CA, Santana IVV, Matsushita MM, Bhat K, Lawler S, Reis RM. Moreno DA, et al. Ther Adv Med Oncol. 2022 Dec 21;14:17588359221127678. doi: 10.1177/17588359221127678. eCollection 2022. Ther Adv Med Oncol. 2022. PMID: 36579028 Free PMC article.
PPRX-1701, a nanoparticle formulation of 6'-bromoindirubin acetoxime, improves delivery and shows efficacy in preclinical GBM models.
Zdioruk M, Jimenez-Macias JL, Nowicki MO, Manz KE, Pennell KD, Koch MS, Finkelberg T, Wu B, Boucher P, Takeda Y, Li W, Piranlioglu R, Ling AL, Chiocca EA, Lawler SE. Zdioruk M, et al. Among authors: lawler se. Cell Rep Med. 2023 May 16;4(5):101019. doi: 10.1016/j.xcrm.2023.101019. Epub 2023 Apr 14. Cell Rep Med. 2023. PMID: 37060903 Free PMC article.
Modulation of blood-tumor barrier transcriptional programs improves intra-tumoral drug delivery and potentiates chemotherapy in GBM.
Jimenez-Macias JL, Vaughn-Beaucaire P, Bharati A, Xu Z, Forrest M, Hong J, Sun M, Schmidt A, Clark J, Hawkins W, Mercado N, Real J, Huntington K, Zdioruk M, Nowicki MO, Cho CF, Wu B, Li W, Logan T, Manz KE, Pennell KD, Fedeles BI, Brodsky AS, Lawler SE. Jimenez-Macias JL, et al. Among authors: lawler se. bioRxiv [Preprint]. 2024 Aug 28:2024.08.26.609797. doi: 10.1101/2024.08.26.609797. bioRxiv. 2024. PMID: 39253453 Free PMC article. Preprint.
97 results