Sharma AK - Search Results

1

Characterization of Anticancer Effects of the Analogs of DJ4, a Novel Selective Inhibitor of ROCK and MRCK Kinases.

Kale VP, Hengst JA, Sharma AK, Golla U, Dovat S, Amin SG, Yun JK, Desai DH. Kale VP, et al. Among authors: sharma ak. Pharmaceuticals (Basel). 2023 Jul 26;16(8):1060. doi: 10.3390/ph16081060. Pharmaceuticals (Basel). 2023. PMID: 37630974 Free PMC article.

2

Targeting mitogen-activated protein kinase/extracellular signal-regulated kinase kinase in the mutant (V600E) B-Raf signaling cascade effectively inhibits melanoma lung metastases.

Sharma A, Tran MA, Liang S, Sharma AK, Amin S, Smith CD, Dong C, Robertson GP. Sharma A, et al. Among authors: sharma ak. Cancer Res. 2006 Aug 15;66(16):8200-9. doi: 10.1158/0008-5472.CAN-06-0809. Cancer Res. 2006. PMID: 16912199 Free PMC article.

3

PBISe, a novel selenium-containing drug for the treatment of malignant melanoma.

Madhunapantula SV, Desai D, Sharma A, Huh SJ, Amin S, Robertson GP. Madhunapantula SV, et al. Mol Cancer Ther. 2008 May;7(5):1297-308. doi: 10.1158/1535-7163.MCT-07-2267. Mol Cancer Ther. 2008. PMID: 18483317

4

Synthesis and anticancer activity comparison of phenylalkyl isoselenocyanates with corresponding naturally occurring and synthetic isothiocyanates.

Sharma AK, Sharma A, Desai D, Madhunapantula SV, Huh SJ, Robertson GP, Amin S. Sharma AK, et al. Among authors: sharma a. J Med Chem. 2008 Dec 25;51(24):7820-6. doi: 10.1021/jm800993r. J Med Chem. 2008. PMID: 19053750 Free PMC article.

5

Targeting Akt3 signaling in malignant melanoma using isoselenocyanates.

Sharma A, Sharma AK, Madhunapantula SV, Desai D, Huh SJ, Mosca P, Amin S, Robertson GP. Sharma A, et al. Among authors: sharma ak. Clin Cancer Res. 2009 Mar 1;15(5):1674-85. doi: 10.1158/1078-0432.CCR-08-2214. Epub 2009 Feb 10. Clin Cancer Res. 2009. PMID: 19208796 Free PMC article.

6

Synthesis and characterization of a novel iNOS/Akt inhibitor Se,Se'-1,4-phenylenebis(1,2-ethanediyl)bisisoselenourea (PBISe)--against colon cancer.

Desai D, Madhunapantula SV, Gowdahalli K, Sharma A, Chandagaludoreswamy R, El-Bayoumy K, Robertson GP, Amin S. Desai D, et al. Bioorg Med Chem Lett. 2010 Mar 15;20(6):2038-43. doi: 10.1016/j.bmcl.2009.09.071. Epub 2009 Sep 22. Bioorg Med Chem Lett. 2010. PMID: 20153642 Free PMC article.

7

Melanoma chemoprevention in skin reconstructs and mouse xenografts using isoselenocyanate-4.

Nguyen N, Sharma A, Nguyen N, Sharma AK, Desai D, Huh SJ, Amin S, Meyers C, Robertson GP. Nguyen N, et al. Among authors: sharma a, sharma ak. Cancer Prev Res (Phila). 2011 Feb;4(2):248-58. doi: 10.1158/1940-6207.CAPR-10-0106. Epub 2010 Nov 19. Cancer Prev Res (Phila). 2011. PMID: 21097713 Free PMC article.

8

Acid ceramidase is upregulated in AML and represents a novel therapeutic target.

Tan SF, Liu X, Fox TE, Barth BM, Sharma A, Turner SD, Awwad A, Dewey A, Doi K, Spitzer B, Shah MV, Morad SA, Desai D, Amin S, Zhu J, Liao J, Yun J, Kester M, Claxton DF, Wang HG, Cabot MC, Schuchman EH, Levine RL, Feith DJ, Loughran TP Jr. Tan SF, et al. Oncotarget. 2016 Dec 13;7(50):83208-83222. doi: 10.18632/oncotarget.13079. Oncotarget. 2016. PMID: 27825124 Free PMC article.

9

SKI-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models.

Hengst JA, Dick TE, Sharma A, Doi K, Hegde S, Tan SF, Geffert LM, Fox TE, Sharma AK, Desai D, Amin S, Kester M, Loughran TP, Paulson RF, Claxton DF, Wang HG, Yun JK. Hengst JA, et al. Among authors: sharma a, sharma ak. Cancer Transl Med. 2017 Jul-Aug;3(4):109-121. doi: 10.4103/ctm.ctm_7_17. Epub 2017 Aug 14. Cancer Transl Med. 2017. PMID: 28890935 Free PMC article.

10

The novel Isatin analog KS99 targets stemness markers in acute myeloid leukemia.

Annageldiyev C, Gowda K, Patel T, Bhattacharya P, Tan SF, Iyer S, Desai D, Dovat S, Feith DJ, Loughran TP Jr, Amin S, Claxton D, Sharma A. Annageldiyev C, et al. Haematologica. 2020 Mar;105(3):687-696. doi: 10.3324/haematol.2018.212886. Epub 2019 May 23. Haematologica. 2020. PMID: 31123028 Free PMC article.

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