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Alvespimycin Exhibits Potential Anti-TGF-β Signaling in the Setting of a Proteasome Activator in Rats with Bleomycin-Induced Pulmonary Fibrosis: A Promising Novel Approach.
Mohammed OA, Abdel-Reheim MA, Saleh LA, Alamri MMS, Alfaifi J, Adam MIE, Farrag AA, AlQahtani AAJ, BinAfif WF, Hashish AA, Abdel-Ghany S, Elmorsy EA, El-Wakeel HS, Doghish AS, Hamad RS, Saber S. Mohammed OA, et al. Among authors: saber s. Pharmaceuticals (Basel). 2023 Aug 9;16(8):1123. doi: 10.3390/ph16081123. Pharmaceuticals (Basel). 2023. PMID: 37631038 Free PMC article.
A Novel Combination Therapy Using Rosuvastatin and Lactobacillus Combats Dextran Sodium Sulfate-Induced Colitis in High-Fat Diet-Fed Rats by Targeting the TXNIP/NLRP3 Interaction and Influencing Gut Microbiome Composition.
Saber S, Abd El-Fattah EE, Yahya G, Gobba NA, Maghmomeh AO, Khodir AE, Mourad AAE, Saad AS, Mohammed HG, Nouh NA, Shata A, Amin NA, Abou El-Rous M, Girgis S, El-Ahwany E, Khalaf EM, El-Kott AF, El-Baz AM. Saber S, et al. Pharmaceuticals (Basel). 2021 Apr 8;14(4):341. doi: 10.3390/ph14040341. Pharmaceuticals (Basel). 2021. PMID: 33917884 Free PMC article.
Combining the HSP90 inhibitor TAS-116 with metformin effectively degrades the NLRP3 and attenuates inflammasome activation in rats: A new management paradigm for ulcerative colitis.
Shaaban AA, Abdelhamid AM, Shaker ME, Cavalu S, Maghiar AM, Alsayegh AA, Babalghith AO, El-Ahwany E, Amin NA, Mohammed OA, Eissa H, Gaafar AGA, Batiha GE, Saber S. Shaaban AA, et al. Among authors: saber s. Biomed Pharmacother. 2022 Sep;153:113247. doi: 10.1016/j.biopha.2022.113247. Epub 2022 Jun 17. Biomed Pharmacother. 2022. PMID: 35724510 Free article.
Carbocisteine as a Modulator of Nrf2/HO-1 and NFκB Interplay in Rats: New Inspiration for the Revival of an Old Drug for Treating Ulcerative Colitis.
Abdelhamid AM, Youssef ME, Cavalu S, Mostafa-Hedeab G, Youssef A, Elazab ST, Ibrahim S, Allam S, Elgharabawy RM, El-Ahwany E, Amin NA, Shata A, Mohammed OA, Ibrahim Abdeldaiem MS, Alhowail A, El-Saber Batiha G, El-Mahmoudy EA, Attia M, Allam A, Zaater MY, Osman MM, Nader M, Taha A, Makarem NA, Saber S. Abdelhamid AM, et al. Among authors: saber s. Front Pharmacol. 2022 Jun 8;13:887233. doi: 10.3389/fphar.2022.887233. eCollection 2022. Front Pharmacol. 2022. PMID: 35754464 Free PMC article.
Ambroxol, a mucolytic agent, boosts HO-1, suppresses NF-κB, and decreases the susceptibility of the inflamed rat colon to apoptosis: A new treatment option for treating ulcerative colitis.
Cavalu S, Sharaf H, Saber S, Youssef ME, Abdelhamid AM, Mourad AAE, Ibrahim S, Allam S, Elgharabawy RM, El-Ahwany E, Amin NA, Shata A, Eldegla M, Atef M, Aboraya M, Mohamed M, Anz N, Elmotelb DA, Gabr F, Elzablawy D, Hamada M, Yehia A, Osama D, Mohammed OA. Cavalu S, et al. Among authors: saber s. FASEB J. 2022 Sep;36(9):e22496. doi: 10.1096/fj.202200749R. FASEB J. 2022. PMID: 35947115
Pimitespib, an HSP90 inhibitor, augments nifuroxazide-induced disruption in the IL-6/STAT3/HIF-1α autocrine loop in rats with bleomycin-challenged lungs: Evolutionary perspective in managing pulmonary fibrosis.
El-Kashef DH, Youssef ME, Nasr M, Alrouji M, Alhajlah S, AlOmeir O, El Adle Khalaf N, Ghaffar DMA, Jamil L, Abdel-Nasser ZM, Ibrahim S, Abdeldaiem MSI, Donia SS, Mohammed OA, Morsy NE, Shata A, Saber S. El-Kashef DH, et al. Among authors: saber s. Biomed Pharmacother. 2022 Sep;153:113487. doi: 10.1016/j.biopha.2022.113487. Epub 2022 Jul 31. Biomed Pharmacother. 2022. PMID: 36076505 Free article.
Canagliflozin-loaded chitosan-hyaluronic acid microspheres modulate AMPK/NF-κB/NLRP3 axis: A new paradigm in the rectal therapy of ulcerative colitis.
Nasr M, Cavalu S, Saber S, Youssef ME, Abdelhamid AM, Elagamy HI, Kamal I, Gaafar AGA, El-Ahwany E, Amin NA, Girgis S, El-Sandarosy R, Mahmoud F, Rizk H, Mansour M, Hasaballah A, El-Rafi AA, El-Azez RA, Essam M, Mohamed D, Essam N, Mohammed OA. Nasr M, et al. Among authors: saber s. Biomed Pharmacother. 2022 Sep;153:113409. doi: 10.1016/j.biopha.2022.113409. Epub 2022 Jul 18. Biomed Pharmacother. 2022. PMID: 36076534 Free article.
Diacetylrhein, an anthraquinone antiarthritic agent, suppresses dextran sodium sulfate-induced inflammation in rats: A possible mechanism for a protective effect against ulcerative colitis.
Zohny MH, Alrouji M, Alhajlah S, AlOmeir O, Ewees MGE, Ghaffar DMA, El Adle Khalaf N, Mohammed OA, Abdeldaiem MSI, El-Bahouty WB, Elrabat A, Zakaria S, Abdel-Nasser ZM, Haleem AA, El-Gharbawy DM, Abdelhady R, Kaddah MMY, Shata A, Saber S. Zohny MH, et al. Among authors: saber s. Biomed Pharmacother. 2022 Oct;154:113651. doi: 10.1016/j.biopha.2022.113651. Epub 2022 Sep 5. Biomed Pharmacother. 2022. PMID: 36081290 Free article.
311 results