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Coxiella co-opts the Glutathione Peroxidase 4 to protect the host cell from oxidative stress-induced cell death.
Loterio RK, Thomas DR, Andrade W, Lee YW, Santos LL, Mascarenhas DPA, Steiner TM, Chiaratto J, Fielden LF, Lopes L, Bird LE, Goldman GH, Stojanovski D, Scott NE, Zamboni DS, Newton HJ. Loterio RK, et al. Among authors: scott ne. Proc Natl Acad Sci U S A. 2023 Sep 5;120(36):e2308752120. doi: 10.1073/pnas.2308752120. Epub 2023 Aug 28. Proc Natl Acad Sci U S A. 2023. PMID: 37639588 Free PMC article.
Glycoproteomics: growing up fast.
Thomas DR, Scott NE. Thomas DR, et al. Among authors: scott ne. Curr Opin Struct Biol. 2021 Jun;68:18-25. doi: 10.1016/j.sbi.2020.10.028. Epub 2020 Dec 2. Curr Opin Struct Biol. 2021. PMID: 33278752 Review.
Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria.
Sharma M, Lingford JP, Petricevic M, Snow AJD, Zhang Y, Järvå MA, Mui JW, Scott NE, Saunders EC, Mao R, Epa R, da Silva BM, Pires DEV, Ascher DB, McConville MJ, Davies GJ, Williams SJ, Goddard-Borger ED. Sharma M, et al. Among authors: scott ne. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2116022119. doi: 10.1073/pnas.2116022119. Proc Natl Acad Sci U S A. 2022. PMID: 35074914 Free PMC article.
Macrophage infectivity potentiator protein, a peptidyl prolyl cis-trans isomerase, essential for Coxiella burnetii growth and pathogenesis.
Debowski AW, Bzdyl NM, Thomas DR, Scott NE, Jenkins CH, Iwasaki J, Kibble EA, Khoo CA, Scheuplein NJ, Seibel PM, Lohr T, Metters G, Bond CS, Norville IH, Stubbs KA, Harmer NJ, Holzgrabe U, Newton HJ, Sarkar-Tyson M. Debowski AW, et al. Among authors: scott ne. PLoS Pathog. 2023 Jul 3;19(7):e1011491. doi: 10.1371/journal.ppat.1011491. eCollection 2023 Jul. PLoS Pathog. 2023. PMID: 37399210 Free PMC article.
A promising bioconjugate vaccine against hypervirulent Klebsiella pneumoniae.
Feldman MF, Mayer Bridwell AE, Scott NE, Vinogradov E, McKee SR, Chavez SM, Twentyman J, Stallings CL, Rosen DA, Harding CM. Feldman MF, et al. Among authors: scott ne. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18655-18663. doi: 10.1073/pnas.1907833116. Epub 2019 Aug 27. Proc Natl Acad Sci U S A. 2019. PMID: 31455739 Free PMC article.
Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice.
Pymm P, Adair A, Chan LJ, Cooney JP, Mordant FL, Allison CC, Lopez E, Haycroft ER, O'Neill MT, Tan LL, Dietrich MH, Drew D, Doerflinger M, Dengler MA, Scott NE, Wheatley AK, Gherardin NA, Venugopal H, Cromer D, Davenport MP, Pickering R, Godfrey DI, Purcell DFJ, Kent SJ, Chung AW, Subbarao K, Pellegrini M, Glukhova A, Tham WH. Pymm P, et al. Among authors: scott ne. Proc Natl Acad Sci U S A. 2021 May 11;118(19):e2101918118. doi: 10.1073/pnas.2101918118. Proc Natl Acad Sci U S A. 2021. PMID: 33893175 Free PMC article.
153 results