Cronin MTD - Search Results

1

Exposure considerations in human safety assessment: Report from an EPAA Partners' Forum.

Cronin MTD, Ball N, Beken S, Bender H, Bercaru O, Caneva L, Corvaro M, Currie RA, Dawson JL, Desert P, Escher SE, Franco A, Irizar A, Mehta JM, Rogiers V, Tremblay RT, Westmoreland C, Maxwell G. Cronin MTD, et al. Regul Toxicol Pharmacol. 2023 Oct;144:105483. doi: 10.1016/j.yrtph.2023.105483. Epub 2023 Aug 26. Regul Toxicol Pharmacol. 2023. PMID: 37640101 Free article.

2

Workshop report on the evaluation of the updated and expanded carcinogen database to support derivation of threshold of toxicological concern values for DNA-reactive carcinogens.

Escher SE, Felter SP, Hollnagel H, Boobis AR, Yang C, Rathman J, Cronin MTD, Batke M. Escher SE, et al. Among authors: cronin mtd. ALTEX. 2023;40(2):341-349. doi: 10.14573/altex.2210111. Epub 2022 Nov 11. ALTEX. 2023. PMID: 36383628 Free article. No abstract available.

3

Metabolism-based category formation for the prioritisation of genotoxicity hazard assessment for plant protection product residues (part 3): Strobilurins.

Enoch SJ, Hasarova Z, Cronin MTD, Bridgwood K, Rao S, Kluxen FM, Frericks M. Enoch SJ, et al. Among authors: cronin mtd. Regul Toxicol Pharmacol. 2023 Oct;144:105484. doi: 10.1016/j.yrtph.2023.105484. Epub 2023 Aug 25. Regul Toxicol Pharmacol. 2023. PMID: 37633329 Free article.

4

Update of the Cancer Potency Database (CPDB) to enable derivations of Thresholds of Toxicological Concern (TTC) for cancer potency.

Yang C, Rathman JF, Ribeiro JV, Batke M, Escher SE, Firman JW, Hobocienski B, Kellner R, Mostrag A, Przybylak KR, Cronin MTD. Yang C, et al. Among authors: cronin mtd. Food Chem Toxicol. 2023 Dec;182:114182. doi: 10.1016/j.fct.2023.114182. Epub 2023 Nov 10. Food Chem Toxicol. 2023. PMID: 37951343 Free article.

5

Metabolism-based category formation for the prioritisation of genotoxicity hazard assessment for plant protection product residues (Part 4): α-Chloroacetamides.

Enoch SJ, Hasarova Z, Cronin MTD, Bridgwood K, Rao S, Kluxen FM, Frericks M. Enoch SJ, et al. Among authors: cronin mtd. Regul Toxicol Pharmacol. 2024 Jun;150:105641. doi: 10.1016/j.yrtph.2024.105641. Epub 2024 May 7. Regul Toxicol Pharmacol. 2024. PMID: 38723937 Free article.

6

Analysis of implicit and explicit uncertainties in QSAR prediction of chemical toxicity: A case study of neurotoxicity.

Achar J, Firman JW, Tran C, Kim D, Cronin MTD, Öberg G. Achar J, et al. Among authors: cronin mtd. Regul Toxicol Pharmacol. 2024 Dec;154:105716. doi: 10.1016/j.yrtph.2024.105716. Epub 2024 Oct 10. Regul Toxicol Pharmacol. 2024. PMID: 39393519 Free article.

7

G × E interactions as a basis for toxicological uncertainty.

Suciu I, Pamies D, Peruzzo R, Wirtz PH, Smirnova L, Pallocca G, Hauck C, Cronin MTD, Hengstler JG, Brunner T, Hartung T, Amelio I, Leist M. Suciu I, et al. Among authors: cronin mtd. Arch Toxicol. 2023 Jul;97(7):2035-2049. doi: 10.1007/s00204-023-03500-9. Epub 2023 Jun 1. Arch Toxicol. 2023. PMID: 37258688 Free PMC article.

8

Guidance for good practice in the application of machine learning in development of toxicological quantitative structure-activity relationships (QSARs).

Belfield SJ, Cronin MTD, Enoch SJ, Firman JW. Belfield SJ, et al. Among authors: cronin mtd. PLoS One. 2023 May 10;18(5):e0282924. doi: 10.1371/journal.pone.0282924. eCollection 2023. PLoS One. 2023. PMID: 37163504 Free PMC article.

9

Utilizing Omics Data for Chemical Grouping.

Viant MR, Barnett RE, Campos B, Colbourne JK, Barnard M, Biales AD, Cronin MTD, Fay KA, Koehrn K, McGarry HF, Sachana M, Hodges G. Viant MR, et al. Among authors: cronin mtd. Environ Toxicol Chem. 2024 Oct;43(10):2094-2104. doi: 10.1002/etc.5959. Epub 2024 Aug 8. Environ Toxicol Chem. 2024. PMID: 39115466 No abstract available.

10

A framework for categorizing sources of uncertainty in in silico toxicology methods: Considerations for chemical toxicity predictions.

Achar J, Firman JW, Cronin MTD, Öberg G. Achar J, et al. Among authors: cronin mtd. Regul Toxicol Pharmacol. 2024 Dec;154:105737. doi: 10.1016/j.yrtph.2024.105737. Epub 2024 Nov 14. Regul Toxicol Pharmacol. 2024. PMID: 39547503 Free article.

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