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Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production.
Reinert LS, Rashidi AS, Tran DN, Katzilieris-Petras G, Hvidt AK, Gohr M, Fruhwürth S, Bodda C, Thomsen MK, Vendelbo MH, Khan AR, Hansen B, Bergström P, Agholme L, Mogensen TH, Christensen MH, Nyengaard JR, Sen GC, Zetterberg H, Verjans GM, Paludan SR. Reinert LS, et al. Among authors: fruhwurth s. J Clin Invest. 2021 Jan 4;131(1):e136824. doi: 10.1172/JCI136824. J Clin Invest. 2021. PMID: 32990676 Free PMC article.
Herpes Simplex Virus 1 and 2 Infections during Differentiation of Human Cortical Neurons.
Bergström P, Trybala E, Eriksson CE, Johansson M, Satir TM, Widéhn S, Fruhwürth S, Michno W, Nazir FH, Hanrieder J, Paludan SR, Agholme L, Zetterberg H, Bergström T. Bergström P, et al. Among authors: fruhwurth s. Viruses. 2021 Oct 14;13(10):2072. doi: 10.3390/v13102072. Viruses. 2021. PMID: 34696502 Free PMC article.
Tyro3 and Gas6 are associated with white matter and myelin integrity in multiple sclerosis.
Rosenstein I, Novakova L, Kvartsberg H, Nordin A, Rasch S, Rembeza E, Sandgren S, Malmeström C, Fruhwürth S, Axelsson M, Blennow K, Zetterberg H, Lycke J. Rosenstein I, et al. Among authors: fruhwurth s. J Neuroinflammation. 2024 Dec 13;21(1):320. doi: 10.1186/s12974-024-03315-0. J Neuroinflammation. 2024. PMID: 39673059 Free PMC article.
Evidence that minocycline treatment confounds the interpretation of neurofilament as a biomarker.
Gentile JE, Heiss C, Corridon TL, Mortberg MA, Fruhwürth S, Guzman K, Grötschel L, Chan K, Herring NC, Janicki T, Nhass R, Sarathy JM, Erickson B, Kunz R, Erickson A, Braun C, Henry KT, Bry L, Arnold SE, Minikel EV, Zetterberg H, Vallabh SM. Gentile JE, et al. Among authors: fruhwurth s. medRxiv [Preprint]. 2024 May 2:2024.05.01.24306384. doi: 10.1101/2024.05.01.24306384. medRxiv. 2024. PMID: 38746398 Free PMC article. Preprint.
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