Wang S - Search Results

1

Discovery of ERD-3111 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader with Strong Antitumor Activity.

Chen Z, Hu B, Rej RK, Wu D, Acharyya RK, Wang M, Xu T, Lu J, Metwally H, Wang Y, McEachern D, Bai L, Gersch CL, Wang M, Zhang W, Li Q, Wen B, Sun D, Rae JM, Wang S. Chen Z, et al. Among authors: wang y, wang m, wang s. J Med Chem. 2023 Sep 14;66(17):12559-12585. doi: 10.1021/acs.jmedchem.3c01186. Epub 2023 Aug 30. J Med Chem. 2023. PMID: 37647546

2

Discovery of substituted 3,4-diphenyl-thiazoles as a novel class of monoamine transporter inhibitors through 3-D pharmacophore search using a new pharmacophore model derived from mazindol.

Enyedy IJ, Wang J, Zaman WA, Johnson KM, Wang S. Enyedy IJ, et al. Among authors: wang j, wang s. Bioorg Med Chem Lett. 2002 Jul 8;12(13):1775-8. doi: 10.1016/s0960-894x(02)00243-3. Bioorg Med Chem Lett. 2002. PMID: 12067559

3

Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.

Varady J, Wu X, Fang X, Min J, Hu Z, Levant B, Wang S. Varady J, et al. Among authors: wang s. J Med Chem. 2003 Oct 9;46(21):4377-92. doi: 10.1021/jm030085p. J Med Chem. 2003. PMID: 14521403

4

Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database.

Nikolovska-Coleska Z, Xu L, Hu Z, Tomita Y, Li P, Roller PP, Wang R, Fang X, Guo R, Zhang M, Lippman ME, Yang D, Wang S. Nikolovska-Coleska Z, et al. Among authors: wang s, wang r. J Med Chem. 2004 May 6;47(10):2430-40. doi: 10.1021/jm030420+. J Med Chem. 2004. PMID: 15115387

5

Design, synthesis, and evaluation of hexahydrobenz[f]isoquinolines as a novel class of dopamine 3 receptor ligands.

Wu X, Chen J, Ji M, Varady J, Levant B, Wang S. Wu X, et al. Among authors: wang s. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5813-6. doi: 10.1016/j.bmcl.2004.09.047. Bioorg Med Chem Lett. 2004. PMID: 15501046

6

Structure-based design, synthesis and biochemical testing of novel and potent Smac peptido-mimetics.

Sun H, Nikolovska-Coleska Z, Chen J, Yang CY, Tomita Y, Pan H, Yoshioka Y, Krajewski K, Roller PP, Wang S. Sun H, et al. Among authors: wang s. Bioorg Med Chem Lett. 2005 Feb 1;15(3):793-7. doi: 10.1016/j.bmcl.2004.11.008. Bioorg Med Chem Lett. 2005. PMID: 15664859

7

(-)-Gossypol enhances response to radiation therapy and results in tumor regression of human prostate cancer.

Xu L, Yang D, Wang S, Tang W, Liu M, Davis M, Chen J, Rae JM, Lawrence T, Lippman ME. Xu L, et al. Among authors: wang s. Mol Cancer Ther. 2005 Feb;4(2):197-205. Mol Cancer Ther. 2005. PMID: 15713891

8

Design, synthesis and structure-activity relationship studies of hexahydropyrazinoquinolines as a novel class of potent and selective dopamine receptor 3 (D3) ligands.

Ji M, Chen J, Ding K, Wu X, Varady J, Levant B, Wang S. Ji M, et al. Among authors: wang s. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1701-5. doi: 10.1016/j.bmcl.2005.01.037. Bioorg Med Chem Lett. 2005. PMID: 15745825

9

Enantiomerically pure hexahydropyrazinoquinolines as potent and selective dopamine 3 subtype receptor ligands.

Ding K, Chen J, Ji M, Wu X, Varady J, Yang CY, Lu Y, Deschamps JR, Levant B, Wang S. Ding K, et al. Among authors: wang s. J Med Chem. 2005 May 5;48(9):3171-81. doi: 10.1021/jm049031l. J Med Chem. 2005. PMID: 15857123

10

Design of novel hexahydropyrazinoquinolines as potent and selective dopamine D3 receptor ligands with improved solubility.

Chen J, Ding K, Levant B, Wang S. Chen J, et al. Among authors: wang s. Bioorg Med Chem Lett. 2006 Jan 15;16(2):443-6. doi: 10.1016/j.bmcl.2005.09.053. Epub 2005 Nov 14. Bioorg Med Chem Lett. 2006. PMID: 16290142

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