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Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser.
Kim H, Lim T, Ha GE, Lee JY, Kim JW, Chang N, Kim SH, Kim KH, Lee J, Cho Y, Kim BW, Abrahamsson A, Kim SH, Kim HJ, Park S, Lee SJ, Park J, Cheong E, Kim BM, Cho HS. Kim H, et al. Among authors: park s, park j. Exp Mol Med. 2023 Sep;55(9):2039-2050. doi: 10.1038/s12276-023-01082-1. Epub 2023 Sep 1. Exp Mol Med. 2023. PMID: 37653040 Free PMC article.
Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency.
Yun JH, Li X, Park JH, Wang Y, Ohki M, Jin Z, Lee W, Park SY, Hu H, Li C, Zatsepin N, Hunter MS, Sierra RG, Koralek J, Yoon CH, Cho HS, Weierstall U, Tang L, Liu H, Lee W. Yun JH, et al. Among authors: park jh, park sy. J Biol Chem. 2019 Jan 18;294(3):794-804. doi: 10.1074/jbc.RA118.004038. Epub 2018 Nov 19. J Biol Chem. 2019. PMID: 30455349 Free PMC article.
Early-stage dynamics of chloride ion-pumping rhodopsin revealed by a femtosecond X-ray laser.
Yun JH, Li X, Yue J, Park JH, Jin Z, Li C, Hu H, Shi Y, Pandey S, Carbajo S, Boutet S, Hunter MS, Liang M, Sierra RG, Lane TJ, Zhou L, Weierstall U, Zatsepin NA, Ohki M, Tame JRH, Park SY, Spence JCH, Zhang W, Schmidt M, Lee W, Liu H. Yun JH, et al. Among authors: park jh, park sy. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2020486118. doi: 10.1073/pnas.2020486118. Proc Natl Acad Sci U S A. 2021. PMID: 33753488 Free PMC article.
Structural insights into the HBV receptor and bile acid transporter NTCP.
Park JH, Iwamoto M, Yun JH, Uchikubo-Kamo T, Son D, Jin Z, Yoshida H, Ohki M, Ishimoto N, Mizutani K, Oshima M, Muramatsu M, Wakita T, Shirouzu M, Liu K, Uemura T, Nomura N, Iwata S, Watashi K, Tame JRH, Nishizawa T, Lee W, Park SY. Park JH, et al. Nature. 2022 Jun;606(7916):1027-1031. doi: 10.1038/s41586-022-04857-0. Epub 2022 May 17. Nature. 2022. PMID: 35580630 Free PMC article.
71,762 results
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