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C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress.
Cicardi ME, Hallgren JH, Mawrie D, Krishnamurthy K, Markandaiah SS, Nelson AT, Kankate V, Anderson EN, Pasinelli P, Pandey UB, Eischen CM, Trotti D. Cicardi ME, et al. Among authors: markandaiah ss. iScience. 2023 Jul 28;26(9):107505. doi: 10.1016/j.isci.2023.107505. eCollection 2023 Sep 15. iScience. 2023. PMID: 37664610 Free PMC article.
Astrocytes drive upregulation of the multidrug resistance transporter ABCB1 (P-Glycoprotein) in endothelial cells of the blood-brain barrier in mutant superoxide dismutase 1-linked amyotrophic lateral sclerosis.
Qosa H, Lichter J, Sarlo M, Markandaiah SS, McAvoy K, Richard JP, Jablonski MR, Maragakis NJ, Pasinelli P, Trotti D. Qosa H, et al. Among authors: markandaiah ss. Glia. 2016 Aug;64(8):1298-313. doi: 10.1002/glia.23003. Epub 2016 May 9. Glia. 2016. PMID: 27158936 Free PMC article.
Inhibiting drug efflux transporters improves efficacy of ALS therapeutics.
Jablonski MR, Markandaiah SS, Jacob D, Meng NJ, Li K, Gennaro V, Lepore AC, Trotti D, Pasinelli P. Jablonski MR, et al. Among authors: markandaiah ss. Ann Clin Transl Neurol. 2014 Dec;1(12):996-1005. doi: 10.1002/acn3.141. Epub 2014 Nov 21. Ann Clin Transl Neurol. 2014. PMID: 25574474 Free PMC article.
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