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Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326).
Ferguson MR, Delgado KN, McBride S, Orbe IC, La Vake CJ, Caimano MJ, Mendez Q, Moraes TF, Schryvers AB, Moody MA, Radolf JD, Weiner MP, Hawley KL. Ferguson MR, et al. Among authors: la vake cj. Front Immunol. 2023 Aug 22;14:1222267. doi: 10.3389/fimmu.2023.1222267. eCollection 2023. Front Immunol. 2023. PMID: 37675118 Free PMC article.
The Treponema pallidum tro operon encodes a multiple metal transporter, a zinc-dependent transcriptional repressor, and a semi-autonomously expressed phosphoglycerate mutase.
Hazlett KR, Rusnak F, Kehres DG, Bearden SW, La Vake CJ, La Vake ME, Maguire ME, Perry RD, Radolf JD. Hazlett KR, et al. Among authors: la vake cj, la vake me. J Biol Chem. 2003 Jun 6;278(23):20687-94. doi: 10.1074/jbc.M300781200. Epub 2003 Mar 31. J Biol Chem. 2003. PMID: 12668673 Free article.
Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-beta.
Cervantes JL, Dunham-Ems SM, La Vake CJ, Petzke MM, Sahay B, Sellati TJ, Radolf JD, Salazar JC. Cervantes JL, et al. Among authors: la vake cj. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3683-8. doi: 10.1073/pnas.1013776108. Epub 2011 Feb 14. Proc Natl Acad Sci U S A. 2011. PMID: 21321205 Free PMC article.
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