Dymock BW - Search Results

1

Local blockade of tacrolimus promotes T-cell-mediated tumor regression in systemically immunosuppressed hosts.

Veitch M, Beaumont K, Pouwer R, Chew HY, Frazer IH, Soyer HP, Campbell S, Dymock BW, Harvey A, Cock TA, Wells JW. Veitch M, et al. Among authors: dymock bw. J Immunother Cancer. 2023 Sep;11(9):e006783. doi: 10.1136/jitc-2023-006783. J Immunother Cancer. 2023. PMID: 37678918 Free PMC article.

2

Predicting Tacrolimus Concentrations in the Skin of Adult Kidney Transplant Recipients: A Feasibility Study.

Sartain F, Viecelli AK, Veitch M, Franklin ME, Dymock BW, Wells JW, Campbell SB. Sartain F, et al. Among authors: dymock bw. Transpl Int. 2024 Jan 23;37:12019. doi: 10.3389/ti.2024.12019. eCollection 2024. Transpl Int. 2024. PMID: 38323070 Free PMC article.

3

Author Correction: AI is a viable alternative to high throughput screening: a 318-target study.

Atomwise AIMS Program. Atomwise AIMS Program. Sci Rep. 2024 Sep 16;14(1):21579. doi: 10.1038/s41598-024-70321-w. Sci Rep. 2024. PMID: 39284864 Free PMC article. No abstract available.

4

AI is a viable alternative to high throughput screening: a 318-target study.

Atomwise AIMS Program. Atomwise AIMS Program. Sci Rep. 2024 Apr 2;14(1):7526. doi: 10.1038/s41598-024-54655-z. Sci Rep. 2024. PMID: 38565852 Free PMC article.

5

Discovery of a potent histone deacetylase (HDAC) 3/6 selective dual inhibitor.

Soumyanarayanan U, Ramanujulu PM, Mustafa N, Haider S, Fang Nee AH, Tong JX, Tan KSW, Chng WJ, Dymock BW. Soumyanarayanan U, et al. Among authors: dymock bw. Eur J Med Chem. 2019 Dec 15;184:111755. doi: 10.1016/j.ejmech.2019.111755. Epub 2019 Oct 7. Eur J Med Chem. 2019. PMID: 31627059

6

Intranasal administration of a stapled relaxin-3 mimetic has anxiolytic- and antidepressant-like activity in rats.

Marwari S, Poulsen A, Shih N, Lakshminarayanan R, Kini RM, Johannes CW, Dymock BW, Dawe GS. Marwari S, et al. Among authors: dymock bw. Br J Pharmacol. 2019 Oct;176(20):3899-3923. doi: 10.1111/bph.14774. Epub 2019 Sep 11. Br J Pharmacol. 2019. PMID: 31220339 Free PMC article.

7

Prodrugs of the cancer cell selective anti-cancer agent (Z)-2-(1H-indol-3-yl)-3-(isoquinolin-5-yl)acrylonitrile (A131) are orally efficacious in a mouse model of resistant colon cancer.

See CS, Kitagawa M, Liao PJ, Lee KH, Wong J, Lee SH, Dymock BW. See CS, et al. Among authors: dymock bw. Bioorg Med Chem Lett. 2019 Jan 15;29(2):216-219. doi: 10.1016/j.bmcl.2018.11.053. Epub 2018 Nov 27. Bioorg Med Chem Lett. 2019. PMID: 30503634

8

Design and synthesis of potent dual inhibitors of JAK2 and HDAC based on fusing the pharmacophores of XL019 and vorinostat.

Chu-Farseeva YY, Mustafa N, Poulsen A, Tan EC, Yen JJY, Chng WJ, Dymock BW. Chu-Farseeva YY, et al. Among authors: dymock bw. Eur J Med Chem. 2018 Oct 5;158:593-619. doi: 10.1016/j.ejmech.2018.09.024. Epub 2018 Sep 11. Eur J Med Chem. 2018. PMID: 30243158

9

Discovery of the cancer cell selective dual acting anti-cancer agent (Z)-2-(1H-indol-3-yl)-3-(isoquinolin-5-yl)acrylonitrile (A131).

See CS, Kitagawa M, Liao PJ, Lee KH, Wong J, Lee SH, Dymock BW. See CS, et al. Among authors: dymock bw. Eur J Med Chem. 2018 Aug 5;156:344-367. doi: 10.1016/j.ejmech.2018.07.011. Epub 2018 Jul 7. Eur J Med Chem. 2018. PMID: 30015072

10

SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling.

Seah KS, Loh JY, Nguyen TTT, Tan HL, Hutchinson PE, Lim KK, Dymock BW, Long YC, Lee EJD, Shen HM, Chen ES. Seah KS, et al. Among authors: dymock bw. Exp Cell Res. 2018 Sep 15;370(2):283-291. doi: 10.1016/j.yexcr.2018.06.029. Epub 2018 Jun 28. Exp Cell Res. 2018. PMID: 29959912

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