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Page 1
The sGC Activator Runcaciguat Has Kidney Protective Effects and Prevents a Decline of Kidney Function in ZSF1 Rats.
Kraehling JR, Benardeau A, Schomber T, Popp L, Vienenkoetter J, Ellinger-Ziegelbauer H, Pavkovic M, Hartmann E, Siudak K, Freyberger A, Hagelschuer I, Mathar I, Hueser J, Hahn MG, Geiss V, Eitner F, Sandner P. Kraehling JR, et al. Among authors: benardeau a. Int J Mol Sci. 2023 Aug 25;24(17):13226. doi: 10.3390/ijms241713226. Int J Mol Sci. 2023. PMID: 37686032 Free PMC article.
Urinary miRNA Profiles in Chronic Kidney Injury-Benefits of Extracellular Vesicle Enrichment and miRNAs as Potential Biomarkers for Renal Fibrosis, Glomerular Injury, and Endothelial Dysfunction.
Petzuch B, Bénardeau A, Hofmeister L, Meyer J, Hartmann E, Pavkovic M, Mathar I, Sandner P, Ellinger-Ziegelbauer H. Petzuch B, et al. Among authors: benardeau a. Toxicol Sci. 2022 Apr 26;187(1):35-50. doi: 10.1093/toxsci/kfac028. Toxicol Sci. 2022. PMID: 35244176
Runcaciguat, a novel soluble guanylate cyclase activator, shows renoprotection in hypertensive, diabetic, and metabolic preclinical models of chronic kidney disease.
Bénardeau A, Kahnert A, Schomber T, Meyer J, Pavkovic M, Kretschmer A, Lawrenz B, Hartmann E, Mathar I, Hueser J, Kraehling JR, Eitner F, Hahn MG, Stasch JP, Sandner P. Bénardeau A, et al. Naunyn Schmiedebergs Arch Pharmacol. 2021 Dec;394(12):2363-2379. doi: 10.1007/s00210-021-02149-4. Epub 2021 Sep 22. Naunyn Schmiedebergs Arch Pharmacol. 2021. PMID: 34550407 Free PMC article.
Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042).
Hahn MG, Lampe T, El Sheikh S, Griebenow N, Woltering E, Schlemmer KH, Dietz L, Gerisch M, Wunder F, Becker-Pelster EM, Mondritzki T, Tinel H, Knorr A, Kern A, Lang D, Hueser J, Schomber T, Benardeau A, Eitner F, Truebel H, Mittendorf J, Kumar V, van den Akker F, Schaefer M, Geiss V, Sandner P, Stasch JP. Hahn MG, et al. Among authors: benardeau a. J Med Chem. 2021 May 13;64(9):5323-5344. doi: 10.1021/acs.jmedchem.0c02154. Epub 2021 Apr 19. J Med Chem. 2021. PMID: 33872507 Free article.
Role of soluble guanylyl cyclase in renal afferent and efferent arterioles.
Wennysia IC, Zhao L, Schomber T, Braun D, Golz S, Summer H, Benardeau A, Lai EY, Lichtenberger FB, Schubert R, Persson PB, Xu MZ, Patzak A. Wennysia IC, et al. Among authors: benardeau a. Am J Physiol Renal Physiol. 2021 Feb 1;320(2):F193-F202. doi: 10.1152/ajprenal.00272.2020. Epub 2020 Dec 28. Am J Physiol Renal Physiol. 2021. PMID: 33356952 Free article.
Semiautomated quantitative image analysis of glomerular immunohistochemistry markers desmin, vimentin, podocin, synaptopodin and WT-1 in acute and chronic rat kidney disease models.
Funk J, Ott V, Herrmann A, Rapp W, Raab S, Riboulet W, Vandjour A, Hainaut E, Benardeau A, Singer T, Jacobsen B. Funk J, et al. Among authors: benardeau a. Histochem Cell Biol. 2016 Mar;145(3):315-26. doi: 10.1007/s00418-015-1391-6. Epub 2015 Dec 15. Histochem Cell Biol. 2016. PMID: 26671788
Therapy with a Selective Cannabinoid Receptor Type 2 Agonist Limits Albuminuria and Renal Injury in Mice with Type 2 Diabetic Nephropathy.
Zoja C, Locatelli M, Corna D, Villa S, Rottoli D, Nava V, Verde R, Piscitelli F, Di Marzo V, Fingerle J, Adam JM, Rothenhaeusler B, Ottaviani G, Bénardeau A, Abbate M, Remuzzi G, Benigni A. Zoja C, et al. Among authors: benardeau a. Nephron. 2016;132(1):59-69. doi: 10.1159/000442679. Epub 2015 Dec 9. Nephron. 2016. PMID: 26646377
40 results