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A novel retinoic acid receptor-γ agonist antagonizes immune checkpoint resistance in lung cancers by altering the tumor immune microenvironment.
Wei CH, Huang L, Kreh B, Liu X, Tyutyunyk-Massey L, Kawakami M, Chen Z, Shi M, Kozlov S, Chan KC, Andresson T, Carrington M, Vuligonda V, Sanders ME, Horowitz A, Hwu P, Peng W, Dmitrovsky E, Liu X. Wei CH, et al. Among authors: tyutyunyk massey l. Sci Rep. 2023 Sep 9;13(1):14907. doi: 10.1038/s41598-023-41690-5. Sci Rep. 2023. PMID: 37689790 Free PMC article.
A Novel CDK2/9 Inhibitor CYC065 Causes Anaphase Catastrophe and Represses Proliferation, Tumorigenesis, and Metastasis in Aneuploid Cancers.
Kawakami M, Mustachio LM, Chen Y, Chen Z, Liu X, Wei CH, Roszik J, Kittai AS, Danilov AV, Zhang X, Fang B, Wang J, Heymach JV, Tyutyunyk-Massey L, Freemantle SJ, Kurie JM, Liu X, Dmitrovsky E. Kawakami M, et al. Among authors: tyutyunyk massey l. Mol Cancer Ther. 2021 Mar;20(3):477-489. doi: 10.1158/1535-7163.MCT-19-0987. Epub 2020 Dec 4. Mol Cancer Ther. 2021. PMID: 33277443 Free PMC article.
NOXA expression is downregulated in human breast cancer undergoing incomplete pathological response and senescence after neoadjuvant chemotherapy.
Al Shboul S, El-Sadoni M, Alhesa A, Abu Shahin N, Abuquteish D, Abu Al Karsaneh O, Alsharaiah E, Ismail MA, Tyutyunyk-Massey L, Alotaibi MR, Neely V, Harada H, Saleh T. Al Shboul S, et al. Among authors: tyutyunyk massey l. Sci Rep. 2023 Sep 23;13(1):15903. doi: 10.1038/s41598-023-42994-2. Sci Rep. 2023. PMID: 37741850 Free PMC article.
Autophagy-deficient breast cancer shows early tumor recurrence and escape from dormancy.
Aqbi HF, Tyutyunyk-Massey L, Keim RC, Butler SE, Thekkudan T, Joshi S, Smith TM, Bandyopadhyay D, Idowu MO, Bear HD, Payne KK, Gewirtz DA, Manjili MH. Aqbi HF, et al. Oncotarget. 2018 Apr 24;9(31):22113-22122. doi: 10.18632/oncotarget.25197. eCollection 2018 Apr 24. Oncotarget. 2018. PMID: 29774126 Free PMC article.
Autophagy-Dependent Sensitization of Triple-Negative Breast Cancer Models to Topoisomerase II Poisons by Inhibition of the Nucleosome Remodeling Factor.
Tyutyunyk-Massey L, Sun Y, Dao N, Ngo H, Dammalapati M, Vaidyanathan A, Singh M, Haqqani S, Haueis J, Finnegan R, Deng X, Kirberger SE, Bos PD, Bandyopadhyay D, Pomerantz WCK, Pommier Y, Gewirtz DA, Landry JW. Tyutyunyk-Massey L, et al. Mol Cancer Res. 2021 Aug;19(8):1338-1349. doi: 10.1158/1541-7786.MCR-20-0743. Epub 2021 Apr 2. Mol Cancer Res. 2021. PMID: 33811160 Free PMC article.
The BET inhibitor/degrader ARV-825 prolongs the growth arrest response to Fulvestrant + Palbociclib and suppresses proliferative recovery in ER-positive breast cancer.
Finnegan RM, Elshazly AM, Patel NH, Tyutyunyk-Massey L, Tran TH, Kumarasamy V, Knudsen ES, Gewirtz DA. Finnegan RM, et al. Among authors: tyutyunyk massey l. Front Oncol. 2023 Jan 18;12:966441. doi: 10.3389/fonc.2022.966441. eCollection 2022. Front Oncol. 2023. PMID: 36741704 Free PMC article.
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