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Page 1
VCP regulates early tau seed amplification via specific cofactors.
Batra S, Vaquer-Alicea JI, Valdez C, Taylor SP, Manon VA, Vega AR, Kashmer OM, Kolay S, Lemoff A, Cairns NJ, White CL, Diamond MI. Batra S, et al. Among authors: kashmer om. Res Sq [Preprint]. 2024 May 22:rs.3.rs-4307848. doi: 10.21203/rs.3.rs-4307848/v1. Res Sq. 2024. PMID: 38826306 Free PMC article. Preprint.
VCP increases or decreases tau seeding using specific cofactors.
Batra S, Vaquer-Alicea J 3rd, Manon VA, Kashmer OM, Lemoff A, Cairns NJ, White CL 3rd, Diamond MI. Batra S, et al. Among authors: kashmer om. bioRxiv [Preprint]. 2023 Aug 30:2023.08.30.555637. doi: 10.1101/2023.08.30.555637. bioRxiv. 2023. PMID: 37693404 Free PMC article. Preprint.
RNA induces unique tau strains and stabilizes Alzheimer's disease seeds.
Zwierzchowski-Zarate AN, Mendoza-Oliva A, Kashmer OM, Collazo-Lopez JE, White CL 3rd, Diamond MI. Zwierzchowski-Zarate AN, et al. Among authors: kashmer om. J Biol Chem. 2022 Aug;298(8):102132. doi: 10.1016/j.jbc.2022.102132. Epub 2022 Jun 11. J Biol Chem. 2022. PMID: 35700826 Free PMC article.
A synthetic heparinoid blocks Tau aggregate cell uptake and amplification.
Stopschinski BE, Thomas TL, Nadji S, Darvish E, Fan L, Holmes BB, Modi AR, Finnell JG, Kashmer OM, Estill-Terpack S, Mirbaha H, Luu HS, Diamond MI. Stopschinski BE, et al. Among authors: kashmer om. J Biol Chem. 2020 Mar 6;295(10):2974-2983. doi: 10.1074/jbc.RA119.010353. Epub 2020 Jan 23. J Biol Chem. 2020. PMID: 31974166 Free PMC article.
Tau monomer encodes strains.
Sharma AM, Thomas TL, Woodard DR, Kashmer OM, Diamond MI. Sharma AM, et al. Among authors: kashmer om. Elife. 2018 Dec 11;7:e37813. doi: 10.7554/eLife.37813. Elife. 2018. PMID: 30526844 Free PMC article.