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VCP increases or decreases tau seeding using specific cofactors.
Batra S, Vaquer-Alicea J 3rd, Manon VA, Kashmer OM, Lemoff A, Cairns NJ, White CL 3rd, Diamond MI. Batra S, et al. Among authors: lemoff a. bioRxiv [Preprint]. 2023 Aug 30:2023.08.30.555637. doi: 10.1101/2023.08.30.555637. bioRxiv. 2023. PMID: 37693404 Free PMC article. Preprint.
Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection.
Spiga L, Fansler RT, Perera YR, Shealy NG, Munneke MJ, Torres TP, David HE, Lemoff A, Ran X, Richardson KL, Pudlo N, Martens EC, Yang ZJ, Skaar EP, Byndloss MX, Chazin WJ, Zhu W. Spiga L, et al. Among authors: lemoff a. bioRxiv [Preprint]. 2023 Jun 26:2023.06.25.546471. doi: 10.1101/2023.06.25.546471. bioRxiv. 2023. Update in: Cell Host Microbe. 2023 Oct 11;31(10):1639-1654.e10. doi: 10.1016/j.chom.2023.08.018. PMID: 37425782 Free PMC article. Updated. Preprint.
ATTRv-V30M Type A amyloid fibrils from heart and nerves exhibit structural homogeneity.
Nguyen BA, Afrin S, Yakubovska A, Singh V, Alicea JV, Kunach P, Singh P, Pekala M, Ahmed Y, Fernandez-Ramirez MDC, Hernandez LOC, Pedretti R, Bassett P, Wang L, Lemoff A, Villalon L, Kluve-Beckerman B, Saelices L. Nguyen BA, et al. Among authors: lemoff a. bioRxiv [Preprint]. 2024 May 14:2024.05.14.594028. doi: 10.1101/2024.05.14.594028. bioRxiv. 2024. Update in: Structure. 2024 Oct 9:S0969-2126(24)00421-0. doi: 10.1016/j.str.2024.09.021. PMID: 38798361 Free PMC article. Updated. Preprint.
ATTRv-V30M amyloid fibrils from heart and nerves exhibit structural homogeneity.
Nguyen BA, Afrin S, Yakubovska A, Singh V, Pedretti R, Bassett P, Pekala M, Alicea JV, Kunach P, Wang L, Lemoff A, Kluve-Beckerman B, Saelices L. Nguyen BA, et al. Among authors: lemoff a. Structure. 2024 Oct 9:S0969-2126(24)00421-0. doi: 10.1016/j.str.2024.09.021. Online ahead of print. Structure. 2024. PMID: 39423808
Identification of potent and reversible piperidine carboxamides that are species-selective orally active proteasome inhibitors to treat malaria.
Lawong A, Gahalawat S, Ray S, Ho N, Han Y, Ward KE, Deng X, Chen Z, Kumar A, Xing C, Hosangadi V, Fairhurst KJ, Tashiro K, Liszczak G, Shackleford DM, Katneni K, Chen G, Saunders J, Crighton E, Casas A, Robinson JJ, Imlay LS, Zhang X, Lemoff A, Zhao Z, Angulo-Barturen I, Jiménez-Díaz MB, Wittlin S, Campbell SF, Fidock DA, Laleu B, Charman SA, Ready JM, Phillips MA. Lawong A, et al. Among authors: lemoff a. Cell Chem Biol. 2024 Aug 15;31(8):1503-1517.e19. doi: 10.1016/j.chembiol.2024.07.001. Epub 2024 Jul 30. Cell Chem Biol. 2024. PMID: 39084225
VCP regulates early tau seed amplification via specific cofactors.
Batra S, Vaquer-Alicea JI, Valdez C, Taylor SP, Manon VA, Vega AR, Kashmer OM, Kolay S, Lemoff A, Cairns NJ, White CL, Diamond MI. Batra S, et al. Among authors: lemoff a. Res Sq [Preprint]. 2024 May 22:rs.3.rs-4307848. doi: 10.21203/rs.3.rs-4307848/v1. Res Sq. 2024. PMID: 38826306 Free PMC article. Preprint.
59 results