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APOE4-promoted gliosis and degeneration in tauopathy are ameliorated by pharmacological inhibition of HMGB1 release.
Koutsodendris N, Blumenfeld J, Agrawal A, Traglia M, Yip O, Rao A, Kim MJ, Nelson MR, Wang YH, Grone B, Hao Y, Thomas R, Zilberter M, Yoon SY, Arriola P, Huang Y. Koutsodendris N, et al. Among authors: zilberter m. Cell Rep. 2023 Oct 31;42(10):113252. doi: 10.1016/j.celrep.2023.113252. Epub 2023 Oct 19. Cell Rep. 2023. PMID: 37863057 Free PMC article.
Neuronal APOE4-induced Early Hippocampal Network Hyperexcitability in Alzheimer's Disease Pathogenesis.
Tabuena DR, Jang SS, Grone B, Yip O, Aery Jones EA, Blumenfeld J, Liang Z, Koutsodendris N, Rao A, Ding L, Zhang AR, Hao Y, Xu Q, Yoon SY, Leon S, Huang Y, Zilberter M. Tabuena DR, et al. Among authors: zilberter m. bioRxiv [Preprint]. 2024 Jul 3:2023.08.28.555153. doi: 10.1101/2023.08.28.555153. bioRxiv. 2024. PMID: 37693533 Free PMC article. Preprint.
Neurons require glucose uptake and glycolysis in vivo.
Li H, Guglielmetti C, Sei YJ, Zilberter M, Le Page LM, Shields L, Yang J, Nguyen K, Tiret B, Gao X, Bennett N, Lo I, Dayton TL, Kampmann M, Huang Y, Rathmell JC, Vander Heiden M, Chaumeil MM, Nakamura K. Li H, et al. Among authors: zilberter m. Cell Rep. 2023 Apr 25;42(4):112335. doi: 10.1016/j.celrep.2023.112335. Epub 2023 Apr 6. Cell Rep. 2023. PMID: 37027294 Free PMC article.
Experimental and real-world evidence supporting the computational repurposing of bumetanide for APOE4-related Alzheimer's disease.
Taubes A, Nova P, Zalocusky KA, Kosti I, Bicak M, Zilberter MY, Hao Y, Yoon SY, Oskotsky T, Pineda S, Chen B, Jones EAA, Choudhary K, Grone B, Balestra ME, Chaudhry F, Paranjpe I, De Freitas J, Koutsodendris N, Chen N, Wang C, Chang W, An A, Glicksberg BS, Sirota M, Huang Y. Taubes A, et al. Among authors: zilberter my. Nat Aging. 2021 Oct;1(10):932-947. doi: 10.1038/s43587-021-00122-7. Epub 2021 Oct 11. Nat Aging. 2021. PMID: 36172600 Free PMC article.
Unifying mechanism behind the onset of acquired epilepsy.
Zilberter Y, Popova I, Zilberter M. Zilberter Y, et al. Among authors: zilberter m. Trends Pharmacol Sci. 2022 Feb;43(2):87-96. doi: 10.1016/j.tips.2021.11.009. Epub 2021 Dec 6. Trends Pharmacol Sci. 2022. PMID: 34887128 Free PMC article. Review.
Author Correction: Experimental and real-world evidence supporting the computational repurposing of bumetanide for APOE4-related Alzheimer's disease.
Taubes A, Nova P, Zalocusky KA, Kosti I, Bicak M, Zilberter MY, Hao Y, Yoon SY, Oskotsky T, Pineda S, Chen B, Aery Jones EA, Choudhary K, Grone B, Balestra ME, Chaudhry F, Paranjpe I, De Freitas J, Koutsodendris N, Chen N, Wang C, Chang W, An A, Glicksberg BS, Sirota M, Huang Y. Taubes A, et al. Among authors: zilberter my. Nat Aging. 2021 Dec;1(12):1202. doi: 10.1038/s43587-021-00144-1. Nat Aging. 2021. PMID: 37117528 No abstract available.
31 results