Scribble influences cyst formation in autosomal-dominant polycystic kidney disease by regulating Hippo signaling pathway.
Xu D, Lv J, He L, Fu L, Hu R, Cao Y, Mei C.
Xu D, et al.
FASEB J. 2018 Aug;32(8):4394-4407. doi: 10.1096/fj.201701376RR. Epub 2018 Mar 12.
FASEB J. 2018.
PMID: 29529391
Altogether, our data indicate that Scribble induces the phosphorylation of YAP and, consequently, influences cyst formation in ADPKD by mediating YAP nucleocytoplasmic shuttling.-Xu, D., Lv, J., He, L., Fu, L., Hu, R., Cao, Y., Mei, C. Scribble influences cyst forma …
Altogether, our data indicate that Scribble induces the phosphorylation of YAP and, consequently, influences cyst formation in ADPKD by medi …