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The transition state for folding of an outer membrane protein.
Huysmans GH, Baldwin SA, Brockwell DJ, Radford SE. Huysmans GH, et al. Among authors: radford se. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4099-104. doi: 10.1073/pnas.0911904107. Epub 2010 Feb 1. Proc Natl Acad Sci U S A. 2010. PMID: 20133664 Free PMC article.
pH-induced molecular shedding drives the formation of amyloid fibril-derived oligomers.
Tipping KW, Karamanos TK, Jakhria T, Iadanza MG, Goodchild SC, Tuma R, Ranson NA, Hewitt EW, Radford SE. Tipping KW, et al. Among authors: radford se. Proc Natl Acad Sci U S A. 2015 May 5;112(18):5691-6. doi: 10.1073/pnas.1423174112. Epub 2015 Apr 20. Proc Natl Acad Sci U S A. 2015. PMID: 25902516 Free PMC article.
Skp is a multivalent chaperone of outer-membrane proteins.
Schiffrin B, Calabrese AN, Devine PWA, Harris SA, Ashcroft AE, Brockwell DJ, Radford SE. Schiffrin B, et al. Among authors: radford se. Nat Struct Mol Biol. 2016 Sep;23(9):786-793. doi: 10.1038/nsmb.3266. Epub 2016 Jul 25. Nat Struct Mol Biol. 2016. PMID: 27455461 Free PMC article.
Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo.
Dobson CL, Devine PW, Phillips JJ, Higazi DR, Lloyd C, Popovic B, Arnold J, Buchanan A, Lewis A, Goodman J, van der Walle CF, Thornton P, Vinall L, Lowne D, Aagaard A, Olsson LL, Ridderstad Wollberg A, Welsh F, Karamanos TK, Pashley CL, Iadanza MG, Ranson NA, Ashcroft AE, Kippen AD, Vaughan TJ, Radford SE, Lowe DC. Dobson CL, et al. Among authors: radford se. Sci Rep. 2016 Dec 20;6:38644. doi: 10.1038/srep38644. Sci Rep. 2016. PMID: 27995962 Free PMC article.
337 results