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Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum.
Bennett JM, Ward KE, Muir RK, Kabeche S, Yoo E, Yeo T, Lam G, Zhang H, Almaliti J, Berger G, Faucher FF, Lin G, Gerwick WH, Yeh E, Fidock DA, Bogyo M. Bennett JM, et al. Among authors: fidock da. ACS Infect Dis. 2023 Oct 13;9(10):2036-2047. doi: 10.1021/acsinfecdis.3c00310. Epub 2023 Sep 15. ACS Infect Dis. 2023. PMID: 37712594 Free PMC article.
Editing the Plasmodium vivax genome, using zinc-finger nucleases.
Moraes Barros RR, Straimer J, Sa JM, Salzman RE, Melendez-Muniz VA, Mu J, Fidock DA, Wellems TE. Moraes Barros RR, et al. Among authors: fidock da. J Infect Dis. 2015 Jan 1;211(1):125-9. doi: 10.1093/infdis/jiu423. Epub 2014 Jul 31. J Infect Dis. 2015. PMID: 25081932 Free PMC article.
Protein Degradation Systems as Antimalarial Therapeutic Targets.
Ng CL, Fidock DA, Bogyo M. Ng CL, et al. Among authors: fidock da. Trends Parasitol. 2017 Sep;33(9):731-743. doi: 10.1016/j.pt.2017.05.009. Epub 2017 Jul 5. Trends Parasitol. 2017. PMID: 28688800 Free PMC article. Review.
Association of a Novel Mutation in the Plasmodium falciparum Chloroquine Resistance Transporter With Decreased Piperaquine Sensitivity.
Agrawal S, Moser KA, Morton L, Cummings MP, Parihar A, Dwivedi A, Shetty AC, Drabek EF, Jacob CG, Henrich PP, Parobek CM, Jongsakul K, Huy R, Spring MD, Lanteri CA, Chaorattanakawee S, Lon C, Fukuda MM, Saunders DL, Fidock DA, Lin JT, Juliano JJ, Plowe CV, Silva JC, Takala-Harrison S. Agrawal S, et al. Among authors: fidock da. J Infect Dis. 2017 Aug 15;216(4):468-476. doi: 10.1093/infdis/jix334. J Infect Dis. 2017. PMID: 28931241 Free PMC article.
Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study.
Llanos-Cuentas A, Casapia M, Chuquiyauri R, Hinojosa JC, Kerr N, Rosario M, Toovey S, Arch RH, Phillips MA, Rozenberg FD, Bath J, Ng CL, Cowell AN, Winzeler EA, Fidock DA, Baker M, Möhrle JJ, Hooft van Huijsduijnen R, Gobeau N, Araeipour N, Andenmatten N, Rückle T, Duparc S. Llanos-Cuentas A, et al. Among authors: fidock da. Lancet Infect Dis. 2018 Aug;18(8):874-883. doi: 10.1016/S1473-3099(18)30309-8. Epub 2018 Jun 13. Lancet Infect Dis. 2018. PMID: 29909069 Free PMC article. Clinical Trial.
301 results