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Neural precursor cell delivery induces acute post-ischemic cerebroprotection, but fails to promote long-term stroke recovery in hyperlipidemic mice due to mechanisms that include pro-inflammatory responses associated with brain hemorrhages.
Yin D, Wang C, Qi Y, Wang YC, Hagemann N, Mohamud Yusuf A, Dzyubenko E, Kaltwasser B, Tertel T, Giebel B, Gunzer M, Popa-Wagner A, Doeppner TR, Hermann DM. Yin D, et al. J Neuroinflammation. 2023 Sep 15;20(1):210. doi: 10.1186/s12974-023-02894-8. J Neuroinflammation. 2023. PMID: 37715288 Free PMC article.
Lipopolysaccharide-induced sepsis-like state compromises post-ischemic neurological recovery, brain tissue survival and remodeling via mechanisms involving microvascular thrombosis and brain T cell infiltration.
Sardari M, Skuljec J, Yin D, Zec K, de Carvalho TS, Albers D, Wang C, Pul R, Popa-Wagner A, Doeppner TR, Kleinschnitz C, Dzyubenko E, Hermann DM. Sardari M, et al. Among authors: yin d. Brain Behav Immun. 2021 Jan;91:627-638. doi: 10.1016/j.bbi.2020.10.015. Epub 2020 Oct 22. Brain Behav Immun. 2021. PMID: 33122024 Free article.
Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice.
Gregorius J, Wang C, Stambouli O, Hussner T, Qi Y, Tertel T, Börger V, Mohamud Yusuf A, Hagemann N, Yin D, Dittrich R, Mouloud Y, Mairinger FD, Magraoui FE, Popa-Wagner A, Kleinschnitz C, Doeppner TR, Gunzer M, Meyer HE, Giebel B, Hermann DM. Gregorius J, et al. Among authors: yin d. Basic Res Cardiol. 2021 Jun 8;116(1):40. doi: 10.1007/s00395-021-00881-9. Basic Res Cardiol. 2021. PMID: 34105014 Free PMC article.
Stroke and myocardial infarction induce neutrophil extracellular trap release disrupting lymphoid organ structure and immunoglobulin secretion.
Tuz AA, Ghosh S, Karsch L, Ttoouli D, Sata SP, Ulusoy Ö, Kraus A, Hoerenbaum N, Wolf JN, Lohmann S, Zwirnlein F, Kaygusuz V, Lakovic V, Tummes HL, Beer A, Gallert M, Thiebes S, Qefalia A, Cibir Z, Antler M, Korste S, Haj Yehia E, Michel L, Rassaf T, Kaltwasser B, Abdelrahman H, Mohamud Yusuf A, Wang C, Yin D, Haeusler L, Lueong S, Richter M, Engel DR, Stenzel M, Soehnlein O, Frank B, Solo-Nomenjanahary M, Ho-Tin-Noé B, Siveke JT, Totzeck M, Hoffmann D, Grüneboom A, Hagemann N, Hasenberg A, Desilles JP, Mazighi M, Sickmann A, Chen J, Hermann DM, Gunzer M, Singh V. Tuz AA, et al. Among authors: yin d. Nat Cardiovasc Res. 2024 May;3(5):525-540. doi: 10.1038/s44161-024-00462-8. Epub 2024 Apr 23. Nat Cardiovasc Res. 2024. PMID: 39195931 Free PMC article.
Safety, Tolerability, and Pharmacokinetics of Long-Acting Broadly Neutralizing HIV-1 Monoclonal Antibody VRC07523LS in Newborn Infants Exposed to HIV-1.
Cunningham CK, McFarland EJ, Muresan P, Capparelli EV, Perlowski C, Johnston B, Bone F, Purdue L, Yin DE, Moye J, Spiegel HML, Majji S, Theron GB, Mujuru HA, Purswani M, Alvarez G, Deville JG, Chambers C, Brown E, Harding PA, Tobin NH, Low K, Gama L; IMPAACT P1112 team. Cunningham CK, et al. Among authors: yin de. J Pediatric Infect Dis Soc. 2025 Jan 16:piaf002. doi: 10.1093/jpids/piaf002. Online ahead of print. J Pediatric Infect Dis Soc. 2025. PMID: 39821046
3,745 results