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Proton-gated coincidence detection is a common feature of GPCR signaling.
Kapolka NJ, Rowe JB, Taghon GJ, Morgan WM, O'Shea CR, Isom DG. Kapolka NJ, et al. Among authors: rowe jb. Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):e2100171118. doi: 10.1073/pnas.2100171118. Epub 2021 Jul 6. Proc Natl Acad Sci U S A. 2021. PMID: 34260394 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33298521
The evolution and mechanism of GPCR proton sensing.
Rowe JB, Kapolka NJ, Taghon GJ, Morgan WM, Isom DG. Rowe JB, et al. J Biol Chem. 2021 Jan-Jun;296:100167. doi: 10.1074/jbc.RA120.016352. Epub 2020 Dec 13. J Biol Chem. 2021. PMID: 33478938 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35555975
Polygenic risk discriminates Lewy body dementia from Alzheimer's disease.
McKeever A, Swann P, Malpetti M, Donaghy PC, Thomas A, Mak E, Carter SF, Tan JHK, Hong YT, Fryer TD, Heslegrave A, Zetterberg H, Su L, Chouliaras L, Rowe JB, O'Brien JT. McKeever A, et al. Among authors: rowe jb. Alzheimers Dement. 2025 Jan 24:e14381. doi: 10.1002/alz.14381. Online ahead of print. Alzheimers Dement. 2025. PMID: 39853853
Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington's disease decades before clinical motor diagnosis.
Scahill RI, Farag M, Murphy MJ, Hobbs NZ, Leocadi M, Langley C, Knights H, Ciosi M, Fayer K, Nakajima M, Thackeray O, Gobom J, Rönnholm J, Weiner S, Hassan YR, Ponraj NKP, Estevez-Fraga C, Parker CS, Malone IB, Hyare H, Long JD, Heslegrave A, Sampaio C, Zhang H, Robbins TW, Zetterberg H, Wild EJ, Rees G, Rowe JB, Sahakian BJ, Monckton DG, Langbehn DR, Tabrizi SJ. Scahill RI, et al. Among authors: rowe jb. Nat Med. 2025 Jan 17. doi: 10.1038/s41591-024-03424-6. Online ahead of print. Nat Med. 2025. PMID: 39825149
495 results