Cao P - Search Results

1

Chronic cough relief by allosteric modulation of P2X3 without taste disturbance.

Guo CR, Zhang ZZ, Zhou X, Sun MY, Li TT, Lei YT, Gao YH, Li QQ, Yue CX, Gao Y, Lin YY, Hao CY, Li CZ, Cao P, Zhu MX, Rong MQ, Wang WH, Yu Y. Guo CR, et al. Among authors: cao p. Nat Commun. 2023 Sep 20;14(1):5844. doi: 10.1038/s41467-023-41495-0. Nat Commun. 2023. PMID: 37730705 Free PMC article.

2

Therapeutic inhibition of keratinocyte TRPV3 sensory channel by local anesthetic dyclonine.

Liu Q, Wang J, Wei X, Hu J, Ping C, Gao Y, Xie C, Wang P, Cao P, Cao Z, Yu Y, Li D, Yao J. Liu Q, et al. Among authors: cao p, cao z. Elife. 2021 Apr 20;10:e68128. doi: 10.7554/eLife.68128. Elife. 2021. PMID: 33876725 Free PMC article.

3

A Buthus martensii Karsch scorpion sting targets Nav1.7 in mice and mimics a phenotype of human chronic pain.

Lu W, Cheng X, Chen J, Wang M, Chen Y, Liu J, Sang M, Zhao N, Yan H, Cheng X, Zhou Q, Ye J, Wang J, Xu E, Tang Z, Zhou X, Rong M, Nilsen EA, Dib-Hajj SD, Waxman SG, Yu Y, Cao P. Lu W, et al. Among authors: cao p. Pain. 2022 Feb 1;163(2):e202-e214. doi: 10.1097/j.pain.0000000000002397. Pain. 2022. PMID: 34252912

4

GSK1702934A and M085 directly activate TRPC6 via a mechanism of stimulating the extracellular cavity formed by the pore helix and transmembrane helix S6.

Yang PL, Li XH, Wang J, Ma XF, Zhou BY, Jiao YF, Wang WH, Cao P, Zhu MX, Li PW, Xiao ZH, Li CZ, Guo CR, Lei YT, Yu Y. Yang PL, et al. Among authors: cao p. J Biol Chem. 2021 Oct;297(4):101125. doi: 10.1016/j.jbc.2021.101125. Epub 2021 Aug 28. J Biol Chem. 2021. PMID: 34461094 Free PMC article.

5

Dynamic recognition of naloxone, morphine and endomorphin1 in the same pocket of µ-opioid receptors.

Zhang X, Sun MY, Zhang X, Guo CR, Lei YT, Wang WH, Fan YZ, Cao P, Li CZ, Wang R, Li XH, Yu Y, Yang XN. Zhang X, et al. Among authors: cao p. Front Mol Biosci. 2022 Aug 16;9:925404. doi: 10.3389/fmolb.2022.925404. eCollection 2022. Front Mol Biosci. 2022. PMID: 36052166 Free PMC article.

6

Vanilloid agonist-mediated activation of TRPV1 channels requires coordinated movement of the S1-S4 bundle rather than a quiescent state.

Sun MY, Zhang X, Yu PC, Liu D, Yang Y, Cui WW, Yang XN, Lei YT, Li XH, Wang WH, Cao P, Wang HS, Zhu MX, Li CZ, Wang R, Fan YZ, Yu Y. Sun MY, et al. Among authors: cao p. Sci Bull (Beijing). 2022 May 30;67(10):1062-1076. doi: 10.1016/j.scib.2022.02.016. Epub 2022 Mar 1. Sci Bull (Beijing). 2022. PMID: 36546250 Free article.

7

Druggable site near the upper vestibule determines the high affinity and P2X3 homotrimer selectivity of sivopixant/S-600918 and its analogue DDTPA.

Wang DP, Zhang M, Li M, Yang XN, Li C, Cao P, Zhu MX, Tian Y, Yu Y, Lei YT. Wang DP, et al. Among authors: cao p. Br J Pharmacol. 2024 Apr;181(8):1203-1220. doi: 10.1111/bph.16273. Epub 2023 Dec 7. Br J Pharmacol. 2024. PMID: 37921202

8

Finely ordered intracellular domain harbors an allosteric site to modulate physiopathological function of P2X3 receptors.

Lin YY, Lu Y, Li CY, Ma XF, Shao MQ, Gao YH, Zhang YQ, Jiang HN, Liu Y, Yang Y, Huang LD, Cao P, Wang HS, Wang J, Yu Y. Lin YY, et al. Among authors: cao p. Nat Commun. 2024 Sep 3;15(1):7652. doi: 10.1038/s41467-024-51815-7. Nat Commun. 2024. PMID: 39227563 Free PMC article.

9

Isolation and pharmacological characterization of a new cytotoxic L-amino acid oxidase from Bungarus multicinctus snake venom.

Lu W, Hu L, Yang J, Sun X, Yan H, Liu J, Chen J, Cheng X, Zhou Q, Yu Y, Wei JF, Cao P. Lu W, et al. Among authors: cao p. J Ethnopharmacol. 2018 Mar 1;213:311-320. doi: 10.1016/j.jep.2017.11.026. Epub 2017 Nov 26. J Ethnopharmacol. 2018. PMID: 29180043

10

Distinct astrocytic modulatory roles in sensory transmission during sleep, wakefulness, and arousal states in freely moving mice.

Wang F, Wang W, Gu S, Qi D, Smith NA, Peng W, Dong W, Yuan J, Zhao B, Mao Y, Cao P, Lu QR, Shapiro LA, Yi SS, Wu E, Huang JH. Wang F, et al. Among authors: cao p. Nat Commun. 2023 Apr 17;14(1):2186. doi: 10.1038/s41467-023-37974-z. Nat Commun. 2023. PMID: 37069258 Free PMC article.

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