Koren I - Search Results

1

Defining E3 ligase-substrate relationships through multiplex CRISPR screening.

Timms RT, Mena EL, Leng Y, Li MZ, Tchasovnikarova IA, Koren I, Elledge SJ. Timms RT, et al. Among authors: koren i. Nat Cell Biol. 2023 Oct;25(10):1535-1545. doi: 10.1038/s41556-023-01229-2. Epub 2023 Sep 21. Nat Cell Biol. 2023. PMID: 37735597 Free PMC article.

2

Autophagy gets a brake: DAP1, a novel mTOR substrate, is activated to suppress the autophagic process.

Koren I, Reem E, Kimchi A. Koren I, et al. Autophagy. 2010 Nov;6(8):1179-80. doi: 10.4161/auto.6.8.13338. Autophagy. 2010. PMID: 20818178 Free PMC article.

3

Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response.

Elia AE, Boardman AP, Wang DC, Huttlin EL, Everley RA, Dephoure N, Zhou C, Koren I, Gygi SP, Elledge SJ. Elia AE, et al. Among authors: koren i. Mol Cell. 2015 Sep 3;59(5):867-81. doi: 10.1016/j.molcel.2015.05.006. Epub 2015 Jun 4. Mol Cell. 2015. PMID: 26051181 Free PMC article.

4

The Eukaryotic Proteome Is Shaped by E3 Ubiquitin Ligases Targeting C-Terminal Degrons.

Koren I, Timms RT, Kula T, Xu Q, Li MZ, Elledge SJ. Koren I, et al. Cell. 2018 Jun 14;173(7):1622-1635.e14. doi: 10.1016/j.cell.2018.04.028. Epub 2018 May 17. Cell. 2018. PMID: 29779948 Free PMC article.

5

A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation.

Timms RT, Zhang Z, Rhee DY, Harper JW, Koren I, Elledge SJ. Timms RT, et al. Among authors: koren i. Science. 2019 Jul 5;365(6448):eaaw4912. doi: 10.1126/science.aaw4912. Science. 2019. PMID: 31273098 Free PMC article.

6

Tying up loose ends: the N-degron and C-degron pathways of protein degradation.

Timms RT, Koren I. Timms RT, et al. Among authors: koren i. Biochem Soc Trans. 2020 Aug 28;48(4):1557-1567. doi: 10.1042/BST20191094. Biochem Soc Trans. 2020. PMID: 32627813 Free PMC article. Review.

7

Molecular basis for arginine C-terminal degron recognition by Cul2^FEM1 E3 ligase.

Chen X, Liao S, Makaros Y, Guo Q, Zhu Z, Krizelman R, Dahan K, Tu X, Yao X, Koren I, Xu C. Chen X, et al. Among authors: koren i. Nat Chem Biol. 2021 Mar;17(3):254-262. doi: 10.1038/s41589-020-00704-3. Epub 2021 Jan 4. Nat Chem Biol. 2021. PMID: 33398168

8

Ubiquitin-independent proteasomal degradation driven by C-degron pathways.

Makaros Y, Raiff A, Timms RT, Wagh AR, Gueta MI, Bekturova A, Guez-Haddad J, Brodsky S, Opatowsky Y, Glickman MH, Elledge SJ, Koren I. Makaros Y, et al. Among authors: koren i. Mol Cell. 2023 Jun 1;83(11):1921-1935.e7. doi: 10.1016/j.molcel.2023.04.023. Epub 2023 May 17. Mol Cell. 2023. PMID: 37201526 Free PMC article.

9

Author Correction: Defining E3 ligase-substrate relationships through multiplex CRISPR screening.

Timms RT, Mena EL, Leng Y, Li MZ, Tchasovnikarova IA, Koren I, Elledge SJ. Timms RT, et al. Among authors: koren i. Nat Cell Biol. 2024 Feb;26(2):305. doi: 10.1038/s41556-023-01336-0. Nat Cell Biol. 2024. PMID: 38114738 Free PMC article. No abstract available.

10

Mechanism of Ψ-Pro/C-degron recognition by the CRL2^FEM1B ubiquitin ligase.

Chen X, Raiff A, Li S, Guo Q, Zhang J, Zhou H, Timms RT, Yao X, Elledge SJ, Koren I, Zhang K, Xu C. Chen X, et al. Among authors: koren i. Nat Commun. 2024 Apr 26;15(1):3558. doi: 10.1038/s41467-024-47890-5. Nat Commun. 2024. PMID: 38670995 Free PMC article.

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