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Page 1
Fcmr regulates mononuclear phagocyte control of anti-tumor immunity.
Kubli SP, Vornholz L, Duncan G, Zhou W, Ramachandran P, Fortin J, Cox M, Han S, Nechanitzky R, Nechanitzky D, Snow BE, Jones L, Li WY, Haight J, Wakeham A, Bray MR, Mak TW. Kubli SP, et al. Among authors: bray mr. Nat Commun. 2019 Jun 18;10(1):2678. doi: 10.1038/s41467-019-10619-w. Nat Commun. 2019. PMID: 31213601 Free PMC article.
Author Correction: Fcmr regulates mononuclear phagocyte control of anti-tumor immunity.
Kubli SP, Vornholz L, Duncan G, Zhou W, Ramachandran P, Fortin J, Cox M, Han S, Nechanitzky R, Nechanitzky D, Snow BE, Jones L, Li WY, Haight J, Wakeham A, Bray MR, Mak TW. Kubli SP, et al. Among authors: bray mr. Nat Commun. 2019 Sep 3;10(1):4069. doi: 10.1038/s41467-019-12106-8. Nat Commun. 2019. PMID: 31481706 Free PMC article.
Polo-like kinase 4 inhibitor CFI-400945 suppresses liver cancer through cell cycle perturbation and eliciting antitumor immunity.
Chan CY, Yuen VW, Chiu DK, Goh CC, Thu KL, Cescon DW, Soria-Bretones I, Law CT, Cheu JW, Lee D, Tse AP, Tan KV, Zhang MS, Wong BP, Wong CM, Khong PL, Ng IO, Bray MR, Mak TW, Yau TC, Wong CC. Chan CY, et al. Among authors: bray mr. Hepatology. 2023 Mar 1;77(3):729-744. doi: 10.1002/hep.32461. Epub 2023 Feb 17. Hepatology. 2023. PMID: 35302667
CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma.
Chan CY, Chiu DK, Yuen VW, Law CT, Wong BP, Thu KL, Cescon DW, Soria-Bretones I, Cheu JW, Lee D, Tse AP, Zhang MS, Tan KV, Ng IO, Khong PL, Yau TC, Bray MR, Mak TW, Wong CC. Chan CY, et al. Among authors: bray mr. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2119514119. doi: 10.1073/pnas.2119514119. Epub 2022 Aug 1. Proc Natl Acad Sci U S A. 2022. PMID: 35914158 Free PMC article.
The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor-resistant ER+ breast cancer with mitotic aberrations.
Soria-Bretones I, Thu KL, Silvester J, Cruickshank J, El Ghamrasni S, Ba-Alawi W, Fletcher GC, Kiarash R, Elliott MJ, Chalmers JJ, Elia AC, Cheng A, Rose AAN, Bray MR, Haibe-Kains B, Mak TW, Cescon DW. Soria-Bretones I, et al. Among authors: bray mr. Sci Adv. 2022 Sep 9;8(36):eabq4293. doi: 10.1126/sciadv.abq4293. Epub 2022 Sep 7. Sci Adv. 2022. PMID: 36070391 Free PMC article.
Preclinical characterization and clinical trial of CFI-400945, a polo-like kinase 4 inhibitor, in patients with relapsed/refractory acute myeloid leukemia and higher-risk myelodysplastic neoplasms.
Murphy T, Mason JM, Leber B, Bray MR, Chan SM, Gupta V, Khalaf D, Maze D, McNamara CJ, Schimmer AD, Schuh AC, Sibai H, Trus M, Valiquette D, Martin K, Nguyen L, Li X, Mak TW, Minden MD, Yee KWL. Murphy T, et al. Among authors: bray mr. Leukemia. 2024 Mar;38(3):502-512. doi: 10.1038/s41375-023-02110-9. Epub 2023 Dec 19. Leukemia. 2024. PMID: 38114624
Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 Is a Potential Effective Treatment for DNA Damage Repair-Deficient Uterine Leiomyosarcoma.
Lee HHY, Chow KL, Wong HS, Chong TY, Wong AST, Cheng GHW, Ko JMK, Siu HC, Yeung MCF, Huen MSY, Tse KY, Bray MR, Mak TW, Leung SY, Ip PPC. Lee HHY, et al. Among authors: bray mr. Clin Cancer Res. 2024 Sep 3;30(17):3904-3918. doi: 10.1158/1078-0432.CCR-23-3720. Clin Cancer Res. 2024. PMID: 38848043 Free PMC article.
Identification of KIFC1 as a putative vulnerability in lung cancers with centrosome amplification.
Zhang C, Wu BZ, Di Ciano-Oliveira C, Wu YF, Khavkine Binstock SS, Soria-Bretones I, Pham NA, Elia AJ, Chari R, Lam WL, Bray MR, Mak TW, Tsao MS, Cescon DW, Thu KL. Zhang C, et al. Among authors: bray mr. Cancer Gene Ther. 2024 Oct;31(10):1559-1570. doi: 10.1038/s41417-024-00824-1. Epub 2024 Aug 24. Cancer Gene Ther. 2024. PMID: 39179685 Free PMC article.
44 results