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Elucidating the direct effects of the novel HDAC inhibitor bocodepsin (OKI-179) on T cells to rationally design regimens for combining with immunotherapy.
Holay N, Somma A, Duchow M, Soleimani M, Capasso A, Kottapalli S, Rios J, Giri U, Diamond J, Schreiber A, Piscopio AD, Van Den Berg C, Eckhardt SG, Triplett TA. Holay N, et al. Among authors: triplett ta. Front Immunol. 2023 Sep 6;14:1260545. doi: 10.3389/fimmu.2023.1260545. eCollection 2023. Front Immunol. 2023. PMID: 37744352 Free PMC article.
Current methods in translational cancer research.
Lee MW, Miljanic M, Triplett T, Ramirez C, Aung KL, Eckhardt SG, Capasso A. Lee MW, et al. Cancer Metastasis Rev. 2021 Mar;40(1):7-30. doi: 10.1007/s10555-020-09931-5. Epub 2020 Sep 14. Cancer Metastasis Rev. 2021. PMID: 32929562 Free PMC article. Review.
First-in-Human Dose-Escalation Study of the Novel Oral Depsipeptide Class I-Targeting HDAC Inhibitor Bocodepsin (OKI-179) in Patients with Advanced Solid Tumors.
Schreiber AR, Kagihara JA, Corr BR, Davis SL, Lieu C, Kim SS, Jimeno A, Camidge DR, Williams J, Heim AM, Martin A, DeMattei JA, Holay N, Triplett TA, Eckhardt SG, Litwiler K, Winkler J, Piscopio AD, Diamond JR. Schreiber AR, et al. Among authors: triplett ta. Cancers (Basel). 2023 Dec 23;16(1):91. doi: 10.3390/cancers16010091. Cancers (Basel). 2023. PMID: 38201519 Free PMC article.
Tumor-associated myeloid cells provide critical support for T-ALL.
Lyu A, Triplett TA, Nam SH, Hu Z, Arasappan D, Godfrey WH, Ames RY, Sarang A, Selden HJ, Lee CH, Georgiou G, Horton TM, Ehrlich LIR. Lyu A, et al. Among authors: triplett ta. Blood. 2020 Oct 15;136(16):1837-1850. doi: 10.1182/blood.2020007145. Blood. 2020. PMID: 32845007 Free article.
Microglia depletion and alcohol: Transcriptome and behavioral profiles.
Warden AS, Triplett TA, Lyu A, Grantham EK, Azzam MM, DaCosta A, Mason S, Blednov YA, Ehrlich LIR, Mayfield RD, Harris RA. Warden AS, et al. Among authors: triplett ta. Addict Biol. 2021 Mar;26(2):e12889. doi: 10.1111/adb.12889. Epub 2020 Mar 16. Addict Biol. 2021. PMID: 32176824 Free PMC article.
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