Herschhorn A - Search Results

1

Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted / founder sensitivity to broadly neutralizing antibodies.

Parthasarathy D, Pothula KR, Dam KA, Ratnapriya S, Benet HC, Parsons R, Huang X, Sammour S, Janowska K, Harris M, Sacco S, Sodroski J, Bridges MD, Hubbell WL, Acharya P, Herschhorn A. Parthasarathy D, et al. Among authors: herschhorn a. bioRxiv [Preprint]. 2023 Dec 5:2023.09.13.557082. doi: 10.1101/2023.09.13.557082. bioRxiv. 2023. Update in: Nat Commun. 2024 Aug 26;15(1):7334. doi: 10.1038/s41467-024-51656-4 PMID: 37745449 Free PMC article. Updated. Preprint.

2

An inducible cell-cell fusion system with integrated ability to measure the efficiency and specificity of HIV-1 entry inhibitors.

Herschhorn A, Finzi A, Jones DM, Courter JR, Sugawara A, Smith AB 3rd, Sodroski JG. Herschhorn A, et al. PLoS One. 2011;6(11):e26731. doi: 10.1371/journal.pone.0026731. Epub 2011 Nov 1. PLoS One. 2011. PMID: 22069466 Free PMC article.

3

Lineage-specific differences between human and simian immunodeficiency virus regulation of gp120 trimer association and CD4 binding.

Finzi A, Pacheco B, Xiang SH, Pancera M, Herschhorn A, Wang L, Zeng X, Desormeaux A, Kwong PD, Sodroski J. Finzi A, et al. Among authors: herschhorn a. J Virol. 2012 Sep;86(17):8974-86. doi: 10.1128/JVI.01076-12. Epub 2012 Jun 13. J Virol. 2012. PMID: 22696649 Free PMC article.

4

Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer.

Mao Y, Wang L, Gu C, Herschhorn A, Xiang SH, Haim H, Yang X, Sodroski J. Mao Y, et al. Among authors: herschhorn a. Nat Struct Mol Biol. 2012 Sep;19(9):893-9. doi: 10.1038/nsmb.2351. Epub 2012 Aug 5. Nat Struct Mol Biol. 2012. PMID: 22864288 Free PMC article.

5

Molecular architecture of the uncleaved HIV-1 envelope glycoprotein trimer.

Mao Y, Wang L, Gu C, Herschhorn A, Désormeaux A, Finzi A, Xiang SH, Sodroski JG. Mao Y, et al. Among authors: herschhorn a. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12438-43. doi: 10.1073/pnas.1307382110. Epub 2013 Jun 11. Proc Natl Acad Sci U S A. 2013. PMID: 23757493 Free PMC article.

6

Loss of a conserved N-linked glycosylation site in the simian immunodeficiency virus envelope glycoprotein V2 region enhances macrophage tropism by increasing CD4-independent cell-to-cell transmission.

Yen PJ, Herschhorn A, Haim H, Salas I, Gu C, Sodroski J, Gabuzda D. Yen PJ, et al. Among authors: herschhorn a. J Virol. 2014 May;88(9):5014-28. doi: 10.1128/JVI.02785-13. Epub 2014 Feb 19. J Virol. 2014. PMID: 24554659 Free PMC article.

7

A broad HIV-1 inhibitor blocks envelope glycoprotein transitions critical for entry.

Herschhorn A, Gu C, Espy N, Richard J, Finzi A, Sodroski JG. Herschhorn A, et al. Nat Chem Biol. 2014 Oct;10(10):845-52. doi: 10.1038/nchembio.1623. Epub 2014 Aug 31. Nat Chem Biol. 2014. PMID: 25174000 Free PMC article.

8

Comparative Analysis of the Glycosylation Profiles of Membrane-Anchored HIV-1 Envelope Glycoprotein Trimers and Soluble gp140.

Go EP, Herschhorn A, Gu C, Castillo-Menendez L, Zhang S, Mao Y, Chen H, Ding H, Wakefield JK, Hua D, Liao HX, Kappes JC, Sodroski J, Desaire H. Go EP, et al. Among authors: herschhorn a. J Virol. 2015 Aug;89(16):8245-57. doi: 10.1128/JVI.00628-15. Epub 2015 May 27. J Virol. 2015. PMID: 26018173 Free PMC article.

9

Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins.

Herschhorn A, Ma X, Gu C, Ventura JD, Castillo-Menendez L, Melillo B, Terry DS, Smith AB 3rd, Blanchard SC, Munro JB, Mothes W, Finzi A, Sodroski J. Herschhorn A, et al. mBio. 2016 Oct 25;7(5):e01598-16. doi: 10.1128/mBio.01598-16. mBio. 2016. PMID: 27795397 Free PMC article.

10

Activation and Inactivation of Primary Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds.

Madani N, Princiotto AM, Zhao C, Jahanbakhshsefidi F, Mertens M, Herschhorn A, Melillo B, Smith AB 3rd, Sodroski J. Madani N, et al. Among authors: herschhorn a. J Virol. 2017 Jan 18;91(3):e01880-16. doi: 10.1128/JVI.01880-16. Print 2017 Feb 1. J Virol. 2017. PMID: 27881646 Free PMC article.

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