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Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted / founder sensitivity to broadly neutralizing antibodies.
Parthasarathy D, Pothula KR, Dam KA, Ratnapriya S, Benet HC, Parsons R, Huang X, Sammour S, Janowska K, Harris M, Sacco S, Sodroski J, Bridges MD, Hubbell WL, Acharya P, Herschhorn A. Parthasarathy D, et al. Among authors: janowska k. bioRxiv [Preprint]. 2023 Dec 5:2023.09.13.557082. doi: 10.1101/2023.09.13.557082. bioRxiv. 2023. Update in: Nat Commun. 2024 Aug 26;15(1):7334. doi: 10.1038/s41467-024-51656-4 PMID: 37745449 Free PMC article. Updated. Preprint.
Controlling the SARS-CoV-2 Spike Glycoprotein Conformation.
Henderson R, Edwards RJ, Mansouri K, Janowska K, Stalls V, Gobeil S, Kopp M, Hsu A, Borgnia M, Parks R, Haynes BF, Acharya P. Henderson R, et al. Among authors: janowska k. bioRxiv [Preprint]. 2020 May 18:2020.05.18.102087. doi: 10.1101/2020.05.18.102087. bioRxiv. 2020. Update in: Nat Struct Mol Biol. 2020 Oct;27(10):925-933. doi: 10.1038/s41594-020-0479-4 PMID: 32511343 Free PMC article. Updated. Preprint.
A glycan cluster on the SARS-CoV-2 spike ectodomain is recognized by Fab-dimerized glycan-reactive antibodies.
Acharya P, Williams W, Henderson R, Janowska K, Manne K, Parks R, Deyton M, Sprenz J, Stalls V, Kopp M, Mansouri K, Edwards RJ, Meyerhoff RR, Oguin T, Sempowski G, Saunders K, Haynes BF. Acharya P, et al. Among authors: janowska k. bioRxiv [Preprint]. 2020 Jun 30:2020.06.30.178897. doi: 10.1101/2020.06.30.178897. bioRxiv. 2020. PMID: 32637953 Free PMC article. Preprint.
Controlling the SARS-CoV-2 spike glycoprotein conformation.
Henderson R, Edwards RJ, Mansouri K, Janowska K, Stalls V, Gobeil SMC, Kopp M, Li D, Parks R, Hsu AL, Borgnia MJ, Haynes BF, Acharya P. Henderson R, et al. Among authors: janowska k. Nat Struct Mol Biol. 2020 Oct;27(10):925-933. doi: 10.1038/s41594-020-0479-4. Epub 2020 Jul 22. Nat Struct Mol Biol. 2020. PMID: 32699321 Free PMC article.
Cold sensitivity of the SARS-CoV-2 spike ectodomain.
Edwards RJ, Mansouri K, Stalls V, Manne K, Watts B, Parks R, Janowska K, Gobeil SMC, Kopp M, Li D, Lu X, Mu Z, Deyton M, Oguin TH, Sprenz J, Williams W, Saunders K, Montefiori D, Sempowski GD, Henderson R, Alam M, Haynes BF, Acharya P. Edwards RJ, et al. Among authors: janowska k. bioRxiv [Preprint]. 2020 Oct 13:2020.07.12.199588. doi: 10.1101/2020.07.12.199588. bioRxiv. 2020. Update in: Nat Struct Mol Biol. 2021 Feb;28(2):128-131. doi: 10.1038/s41594-020-00547-5 PMID: 32699852 Free PMC article. Updated. Preprint.
D614G mutation alters SARS-CoV-2 spike conformational dynamics and protease cleavage susceptibility at the S1/S2 junction.
Gobeil S, Janowska K, McDowell S, Mansouri K, Parks R, Manne K, Stalls V, Kopp M, Henderson R, Edwards RJ, Haynes BF, Acharya P. Gobeil S, et al. Among authors: janowska k. bioRxiv [Preprint]. 2020 Oct 12:2020.10.11.335299. doi: 10.1101/2020.10.11.335299. bioRxiv. 2020. Update in: Cell Rep. 2021 Jan 12;34(2):108630. doi: 10.1016/j.celrep.2020.108630 PMID: 33052347 Free PMC article. Updated. Preprint.
Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions.
Shiakolas AR, Kramer KJ, Wrapp D, Richardson SI, Schäfer A, Wall S, Wang N, Janowska K, Pilewski KA, Venkat R, Parks R, Manamela NP, Raju N, Fechter EF, Holt CM, Suryadevara N, Chen RE, Martinez DR, Nargi RS, Sutton RE, Ledgerwood JE, Graham BS, Diamond MS, Haynes BF, Acharya P, Carnahan RH, Crowe JE, Baric RS, Morris L, McLellan JS, Georgiev IS. Shiakolas AR, et al. Among authors: janowska k. bioRxiv [Preprint]. 2020 Dec 20:2020.12.20.414748. doi: 10.1101/2020.12.20.414748. bioRxiv. 2020. Update in: Cell Rep Med. 2021 Jun 15;2(6):100313. doi: 10.1016/j.xcrm.2021.100313 PMID: 33398266 Free PMC article. Updated. Preprint.
Cold sensitivity of the SARS-CoV-2 spike ectodomain.
Edwards RJ, Mansouri K, Stalls V, Manne K, Watts B, Parks R, Janowska K, Gobeil SMC, Kopp M, Li D, Lu X, Mu Z, Deyton M, Oguin TH 3rd, Sprenz J, Williams W, Saunders KO, Montefiori D, Sempowski GD, Henderson R, Munir Alam S, Haynes BF, Acharya P. Edwards RJ, et al. Among authors: janowska k. Nat Struct Mol Biol. 2021 Feb;28(2):128-131. doi: 10.1038/s41594-020-00547-5. Epub 2021 Jan 5. Nat Struct Mol Biol. 2021. PMID: 33402708 Free PMC article.
47 results