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Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted / founder sensitivity to broadly neutralizing antibodies.
Parthasarathy D, Pothula KR, Dam KA, Ratnapriya S, Benet HC, Parsons R, Huang X, Sammour S, Janowska K, Harris M, Sacco S, Sodroski J, Bridges MD, Hubbell WL, Acharya P, Herschhorn A. Parthasarathy D, et al. Among authors: sodroski j. bioRxiv [Preprint]. 2023 Dec 5:2023.09.13.557082. doi: 10.1101/2023.09.13.557082. bioRxiv. 2023. Update in: Nat Commun. 2024 Aug 26;15(1):7334. doi: 10.1038/s41467-024-51656-4 PMID: 37745449 Free PMC article. Updated. Preprint.
Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern.
Li W, Chen Y, Prévost J, Ullah I, Lu M, Gong SY, Tauzin A, Gasser R, Vézina D, Anand SP, Goyette G, Chaterjee D, Ding S, Tolbert WD, Grunst MW, Bo Y, Zhang S, Richard J, Zhou F, Huang RK, Esser L, Zeher A, Côté M, Kumar P, Sodroski J, Xia D, Uchil PD, Pazgier M, Finzi A, Mothes W. Li W, et al. Among authors: sodroski j. bioRxiv [Preprint]. 2021 Aug 3:2021.08.02.454546. doi: 10.1101/2021.08.02.454546. bioRxiv. 2021. Update in: Cell Rep. 2022 Jan 11;38(2):110210. doi: 10.1016/j.celrep.2021.110210 PMID: 34373853 Free PMC article. Updated. Preprint.
The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC.
Richard J, Grunst MW, Niu L, Díaz-Salinas MA, Tolbert WD, Marchitto L, Zhou F, Bourassa C, Yang D, Chiu TJ, Chen HC, Benlarbi M; Guillaume-Beaudoin-Buissières; Gottumukkala S, Li W, Dionne K, Bélanger É, Chatterjee D, Medjahed H, Hendrickson WA, Sodroski J, Lang ZC, Morton AJ, Huang RK, Matthies D, Smith AB 3rd, Mothes W, Munro JB, Pazgier M, Finzi A. Richard J, et al. Among authors: sodroski j. bioRxiv [Preprint]. 2024 Aug 27:2024.08.27.609961. doi: 10.1101/2024.08.27.609961. bioRxiv. 2024. PMID: 39253431 Free PMC article. Preprint.
Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted/founder sensitivity to broadly neutralizing antibodies.
Parthasarathy D, Pothula KR, Ratnapriya S, Cervera Benet H, Parsons R, Huang X, Sammour S, Janowska K, Harris M, Sodroski J, Acharya P, Herschhorn A. Parthasarathy D, et al. Among authors: sodroski j. Nat Commun. 2024 Aug 26;15(1):7334. doi: 10.1038/s41467-024-51656-4. Nat Commun. 2024. PMID: 39187497 Free PMC article.
500 results