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The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A1 and A2A receptor affinity and selectivity profiles.
Squarcialupi L, Betti M, Catarzi D, Varano F, Falsini M, Ravani A, Pasquini S, Vincenzi F, Salmaso V, Sturlese M, Varani K, Moro S, Colotta V. Squarcialupi L, et al. Among authors: pasquini s. J Enzyme Inhib Med Chem. 2017 Dec;32(1):248-263. doi: 10.1080/14756366.2016.1247060. J Enzyme Inhib Med Chem. 2017. PMID: 28114825 Free PMC article.
Development of novel pyridazinone-based adenosine receptor ligands.
Catarzi D, Varano F, Falsini M, Varani K, Vincenzi F, Pasquini S, Dal Ben D, Colotta V. Catarzi D, et al. Among authors: pasquini s. Bioorg Med Chem Lett. 2018 May 15;28(9):1484-1489. doi: 10.1016/j.bmcl.2018.03.086. Epub 2018 Mar 30. Bioorg Med Chem Lett. 2018. PMID: 29627261
99 results