Hu AK - Search Results

1

Islet-autoreactive CD4+ T cells are linked with response to alefacept in type 1 diabetes.

Balmas E, Chen J, Hu AK, DeBerg HA, Rosasco MG, Gersuk VH, Serti E, Speake C, Greenbaum CJ, Nepom GT, Linsley PS, Cerosaletti K. Balmas E, et al. Among authors: hu ak. JCI Insight. 2023 Nov 8;8(21):e167881. doi: 10.1172/jci.insight.167881. JCI Insight. 2023. PMID: 37751304 Free PMC article.

2

Conserved IFN Signature between Adult and Pediatric Eosinophilic Esophagitis.

Ruffner MA, Hu A, Dilollo J, Benocek K, Shows D, Gluck M, Spergel JM, Ziegler SF, Hill DA, Cerosaletti K. Ruffner MA, et al. J Immunol. 2021 Mar 15;206(6):1361-1371. doi: 10.4049/jimmunol.2000973. Epub 2021 Feb 8. J Immunol. 2021. PMID: 33558373 Free PMC article.

3

Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes.

Linsley PS, Barahmand-Pour-Whitman F, Balmas E, DeBerg HA, Flynn KJ, Hu AK, Rosasco MG, Chen J, O'Rourke C, Serti E, Gersuk VH, Motwani K, Seay HR, Brusko TM, Kwok WW, Speake C, Greenbaum CJ, Nepom GT, Cerosaletti K. Linsley PS, et al. Among authors: hu ak. JCI Insight. 2021 Nov 22;6(22):e151349. doi: 10.1172/jci.insight.151349. JCI Insight. 2021. PMID: 34806648 Free PMC article.

4

Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity.

Lambert K, Moo KG, Arnett A, Goel G, Hu A, Flynn KJ, Speake C, Wiedeman AE, Gersuk VH, Linsley PS, Greenbaum CJ, Long SA, Partridge R, Buckner JH, Khor B. Lambert K, et al. Sci Transl Med. 2022 Jan 12;14(627):eabi4888. doi: 10.1126/scitranslmed.abi4888. Epub 2022 Jan 12. Sci Transl Med. 2022. PMID: 35020411 Free PMC article.

5

IL-6-targeted therapies to block the cytokine or its receptor drive distinct alterations in T cell function.

Speake C, Habib T, Lambert K, Hundhausen C, Lord S, Dufort MJ, Skinner SO, Hu A, Kinsman M, Jones BE, Maerz MD, Tatum M, Hocking AM, Nepom GT, Greenbaum CJ, Buckner JH. Speake C, et al. JCI Insight. 2022 Nov 22;7(22):e159436. doi: 10.1172/jci.insight.159436. JCI Insight. 2022. PMID: 36282595 Free PMC article.

6

Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy.

Calise J, DeBerg H, Garabatos N, Khosa S, Bajzik V, Calderon LB, Aldridge K, Rosasco M, Ferslew BC, Zhu T, Smulders R, Wheatley LM, Laidlaw TM, Qin T, Chichili GR, Adelman DC, Farrington M, Robinson D, Jeong D, Jones SM, Sanda S, Larson D, Kwok WW, Baloh C, Nepom GT, Wambre E; IMPACT. Calise J, et al. J Allergy Clin Immunol. 2023 Jul;152(1):155-166.e9. doi: 10.1016/j.jaci.2023.03.020. Epub 2023 Mar 30. J Allergy Clin Immunol. 2023. PMID: 37003475 Free PMC article.

7

A phase 2 randomized trial with autologous polyclonal expanded regulatory T cells in children with new-onset type 1 diabetes.

Bender C, Wiedeman AE, Hu A, Ylescupidez A, Sietsema WK, Herold KC, Griffin KJ, Gitelman SE, Long SA; T-Rex Study Group†; T-Rex Clinical Study Group. Bender C, et al. Sci Transl Med. 2024 May 8;16(746):eadn2404. doi: 10.1126/scitranslmed.adn2404. Epub 2024 May 8. Sci Transl Med. 2024. PMID: 38718135 Clinical Trial.

8

Identification of a novel PDC-E2 epitope in primary biliary cholangitis: Application for engineered Treg therapy.

Tewari R, Yang SJ, McClain ED, Hu A, Mortensen E, DeSchmidt A, Chen J, Kancharla A, Singh AK, James EA, Burman BE, Siddique A, Rawlings DJ, Patel C, Cerosaletti K, Buckner JH. Tewari R, et al. Among authors: hu a. J Autoimmun. 2024 Dec;149:103327. doi: 10.1016/j.jaut.2024.103327. Epub 2024 Oct 30. J Autoimmun. 2024. PMID: 39476446

9

CBLB Deficiency in Human CD4⁺ T Cells Results in Resistance to T Regulatory Suppression through Multiple Mechanisms.

Song J, Anderson W, Hu A, Obata-Ninomiya K, Ziegler SF, Rawlings DJ, Buckner JH. Song J, et al. J Immunol. 2022 Oct 1;209(7):1260-1271. doi: 10.4049/jimmunol.2200219. Epub 2022 Sep 7. J Immunol. 2022. PMID: 36165179

10

Regulatory T cells suppress CD4+ effector T cell activation by controlling protein synthesis.

So L, Obata-Ninomiya K, Hu A, Muir VS, Takamori A, Song J, Buckner JH, Savan R, Ziegler SF. So L, et al. J Exp Med. 2023 Mar 6;220(3):e20221676. doi: 10.1084/jem.20221676. Epub 2023 Jan 4. J Exp Med. 2023. PMID: 36598533 Free PMC article.

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