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Challenges and Opportunities for In Vitro-In Vivo Extrapolation of Aldehyde Oxidase-Mediated Clearance: Toward a Roadmap for Quantitative Translation.
Izat N, Bolleddula J, Abbasi A, Cheruzel L, Jones RS, Moss D, Ortega-Muro F, Parmentier Y, Peterkin VC, Tian DD, Venkatakrishnan K, Zientek MA, Barber J, Houston JB, Galetin A, Scotcher D. Izat N, et al. Among authors: barber j. Drug Metab Dispos. 2023 Dec;51(12):1591-1606. doi: 10.1124/dmd.123.001436. Epub 2023 Sep 26. Drug Metab Dispos. 2023. PMID: 37751998
Toward a Consensus on Applying Quantitative Liquid Chromatography-Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper.
Prasad B, Achour B, Artursson P, Hop CECA, Lai Y, Smith PC, Barber J, Wisniewski JR, Spellman D, Uchida Y, Zientek MA, Unadkat JD, Rostami-Hodjegan A. Prasad B, et al. Among authors: barber j. Clin Pharmacol Ther. 2019 Sep;106(3):525-543. doi: 10.1002/cpt.1537. Epub 2019 Jul 26. Clin Pharmacol Ther. 2019. PMID: 31175671 Free PMC article.
Scaling Factors for Clearance in Adult Liver Cirrhosis.
El-Khateeb E, Achour B, Scotcher D, Al-Majdoub ZM, Athwal V, Barber J, Rostami-Hodjegan A. El-Khateeb E, et al. Among authors: barber j. Drug Metab Dispos. 2020 Dec;48(12):1271-1282. doi: 10.1124/dmd.120.000152. Epub 2020 Sep 25. Drug Metab Dispos. 2020. PMID: 32978222 Clinical Trial.
Label-Free Quantitative Proteomics and Substrate-Based Mass Spectrometry Imaging of Xenobiotic Metabolizing Enzymes in Ex Vivo Human Skin and a Human Living Skin Equivalent Model.
Couto N, Newton JRA, Russo C, Karunakaran E, Achour B, Al-Majdoub ZM, Sidaway J, Rostami-Hodjegan A, Clench MR, Barber J. Couto N, et al. Among authors: barber j. Drug Metab Dispos. 2021 Jan;49(1):39-52. doi: 10.1124/dmd.120.000168. Epub 2020 Nov 2. Drug Metab Dispos. 2021. PMID: 33139459
2,030 results