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Enhancement of Radiation Therapy through Blockade of the Immune Checkpoint, V-domain Ig Suppressor of T Cell Activation (VISTA), in Melanoma and Adenocarcinoma Murine Models.
Duval KEA, Tavakkoli AD, Kheirollah A, Soderholm HE, Demidenko E, Lines JL, Croteau W, Zhang SC, Wagner RJ, Aulwes E, Noelle RJ, Hoopes PJ. Duval KEA, et al. Among authors: lines jl. Int J Mol Sci. 2023 Sep 6;24(18):13742. doi: 10.3390/ijms241813742. Int J Mol Sci. 2023. PMID: 37762046 Free PMC article.
VISTA is an immune checkpoint molecule for human T cells.
Lines JL, Pantazi E, Mak J, Sempere LF, Wang L, O'Connell S, Ceeraz S, Suriawinata AA, Yan S, Ernstoff MS, Noelle R. Lines JL, et al. Cancer Res. 2014 Apr 1;74(7):1924-32. doi: 10.1158/0008-5472.CAN-13-1504. Cancer Res. 2014. PMID: 24691993 Free PMC article.
VISTA Regulates the Development of Protective Antitumor Immunity.
Le Mercier I, Chen W, Lines JL, Day M, Li J, Sergent P, Noelle RJ, Wang L. Le Mercier I, et al. Among authors: lines jl. Cancer Res. 2014 Apr 1;74(7):1933-44. doi: 10.1158/0008-5472.CAN-13-1506. Cancer Res. 2014. PMID: 24691994 Free PMC article.
Immunoregulatory functions of VISTA.
Nowak EC, Lines JL, Varn FS, Deng J, Sarde A, Mabaera R, Kuta A, Le Mercier I, Cheng C, Noelle RJ. Nowak EC, et al. Among authors: lines jl. Immunol Rev. 2017 Mar;276(1):66-79. doi: 10.1111/imr.12525. Immunol Rev. 2017. PMID: 28258694 Free PMC article. Review.
Hypoxia-Induced VISTA Promotes the Suppressive Function of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment.
Deng J, Li J, Sarde A, Lines JL, Lee YC, Qian DC, Pechenick DA, Manivanh R, Le Mercier I, Lowrey CH, Varn FS, Cheng C, Leib DA, Noelle RJ, Mabaera R. Deng J, et al. Among authors: lines jl. Cancer Immunol Res. 2019 Jul;7(7):1079-1090. doi: 10.1158/2326-6066.CIR-18-0507. Epub 2019 May 14. Cancer Immunol Res. 2019. PMID: 31088847 Free PMC article.
Defining the Signature of VISTA on Myeloid Cell Chemokine Responsiveness.
Broughton TWK, ElTanbouly MA, Schaafsma E, Deng J, Sarde A, Croteau W, Li J, Nowak EC, Mabaera R, Smits NC, Kuta A, Noelle RJ, Lines JL. Broughton TWK, et al. Among authors: lines jl. Front Immunol. 2019 Nov 19;10:2641. doi: 10.3389/fimmu.2019.02641. eCollection 2019. Front Immunol. 2019. PMID: 31803182 Free PMC article.
24 results