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VWF-ADAMTS13 axis dysfunction in children with sickle cell disease treated with hydroxycarbamide vs blood transfusion.
Fogarty H, Ahmad A, Atiq F, Doherty D, Ward S, Karampini E, Rehill A, Leon G, Byrne C, Geoghegan R, Conroy H, Byrne M, Budde U, Schneppenheim S, Sheehan C, Ngwenya N, Baker RI, Preston RJS, Tuohy E, McMahon C, O'Donnell JS. Fogarty H, et al. Among authors: byrne c, byrne m. Blood Adv. 2023 Nov 28;7(22):6974-6989. doi: 10.1182/bloodadvances.2023010824. Blood Adv. 2023. PMID: 37773926 Free PMC article.
Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels.
Lavin M, Aguila S, Schneppenheim S, Dalton N, Jones KL, O'Sullivan JM, O'Connell NM, Ryan K, White B, Byrne M, Rafferty M, Doyle MM, Nolan M, Preston RJS, Budde U, James P, Di Paola J, O'Donnell JS. Lavin M, et al. Among authors: byrne m. Blood. 2017 Nov 23;130(21):2344-2353. doi: 10.1182/blood-2017-05-786699. Epub 2017 Sep 15. Blood. 2017. PMID: 28916584 Free PMC article. Clinical Trial.
Significant gynecological bleeding in women with low von Willebrand factor levels.
Lavin M, Aguila S, Dalton N, Nolan M, Byrne M, Ryan K, White B, O'Connell NM, O'Sullivan JM, Di Paola J, James PD, O'Donnell JS. Lavin M, et al. Among authors: byrne m. Blood Adv. 2018 Jul 24;2(14):1784-1791. doi: 10.1182/bloodadvances.2018017418. Blood Adv. 2018. PMID: 30042144 Free PMC article. Clinical Trial.
Increased galactose expression and enhanced clearance in patients with low von Willebrand factor.
Aguila S, Lavin M, Dalton N, Patmore S, Chion A, Trahan GD, Jones KL, Keenan C, Brophy TM, O'Connell NM, Ryan K, Byrne M, Nolan M, Patel A, Preston RJS, James P, Di Paola J, O'Sullivan JM, O'Donnell JS. Aguila S, et al. Among authors: byrne m. Blood. 2019 Apr 4;133(14):1585-1596. doi: 10.1182/blood-2018-09-874636. Epub 2019 Feb 15. Blood. 2019. PMID: 30770394 Free article.
ADAMTS13 regulation of VWF multimer distribution in severe COVID-19.
Ward SE, Fogarty H, Karampini E, Lavin M, Schneppenheim S, Dittmer R, Morrin H, Glavey S, Ni Cheallaigh C, Bergin C, Martin-Loeches I, Mallon PW, Curley GF, Baker RI, Budde U, O'Sullivan JM, O'Donnell JS; Irish COVID-19 Vasculopathy Study (iCVS) investigators. Ward SE, et al. J Thromb Haemost. 2021 Aug;19(8):1914-1921. doi: 10.1111/jth.15409. Epub 2021 Jun 20. J Thromb Haemost. 2021. PMID: 34053187 Free PMC article.
Persistent endotheliopathy in the pathogenesis of long COVID syndrome.
Fogarty H, Townsend L, Morrin H, Ahmad A, Comerford C, Karampini E, Englert H, Byrne M, Bergin C, O'Sullivan JM, Martin-Loeches I, Nadarajan P, Bannan C, Mallon PW, Curley GF, Preston RJS, Rehill AM, McGonagle D, Ni Cheallaigh C, Baker RI, Renné T, Ward SE, O'Donnell JS; Irish COVID-19 Vasculopathy Study (iCVS) investigators. Fogarty H, et al. Among authors: byrne m. J Thromb Haemost. 2021 Oct;19(10):2546-2553. doi: 10.1111/jth.15490. Epub 2021 Sep 12. J Thromb Haemost. 2021. PMID: 34375505 Free PMC article.
Sustained VWF-ADAMTS-13 axis imbalance and endotheliopathy in long COVID syndrome is related to immune dysfunction.
Fogarty H, Ward SE, Townsend L, Karampini E, Elliott S, Conlon N, Dunne J, Kiersey R, Naughton A, Gardiner M, Byrne M, Bergin C, O'Sullivan JM, Martin-Loeches I, Nadarajan P, Bannan C, Mallon PW, Curley GF, Preston RJS, Rehill AM, Baker RI, Cheallaigh CN, O'Donnell JS; Irish COVID-19 Vasculopathy Study (iCVS) Investigators. Fogarty H, et al. Among authors: byrne m. J Thromb Haemost. 2022 Oct;20(10):2429-2438. doi: 10.1111/jth.15830. Epub 2022 Aug 4. J Thromb Haemost. 2022. PMID: 35875995 Free PMC article.
Endothelial cell activation, Weibel-Palade body secretion, and enhanced angiogenesis in severe COVID-19.
Karampini E, Fogarty H, Elliott S, Morrin H, Bergin C, O'Sullivan JM, Byrne M, Martin-Loeches I, Mallon PW, Curley GF, Glavey S, Baker RI, Lavin M, Preston RJS, Cheallaigh CN, Ward SE, O'Donnell JS. Karampini E, et al. Among authors: byrne m. Res Pract Thromb Haemost. 2023 Feb;7(2):100085. doi: 10.1016/j.rpth.2023.100085. Epub 2023 Feb 14. Res Pract Thromb Haemost. 2023. PMID: 36817284 Free PMC article.
Von Willebrand factor propeptide in severe coronavirus disease 2019 (COVID-19): evidence of acute and sustained endothelial cell activation.
Ward SE, Curley GF, Lavin M, Fogarty H, Karampini E, McEvoy NL, Clarke J, Boylan M, Alalqam R, Worrall AP, Kelly C, de Barra E, Glavey S, Ni Cheallaigh C, Bergin C, Martin-Loeches I, Townsend L, Mallon PW, O'Sullivan JM, O'Donnell JS; Irish COVID-19 Vasculopathy Study (ICVS) Investigators. Ward SE, et al. Br J Haematol. 2021 Feb;192(4):714-719. doi: 10.1111/bjh.17273. Epub 2020 Dec 16. Br J Haematol. 2021. PMID: 33326604 Free article.
2,347 results