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Page 1
Senescence-associated inflammation and inhibition of adipogenesis in subcutaneous fat in Werner syndrome.
Sawada D, Kato H, Kaneko H, Kinoshita D, Funayama S, Minamizuka T, Takasaki A, Igarashi K, Koshizaka M, Takada-Watanabe A, Nakamura R, Aono K, Yamaguchi A, Teramoto N, Maeda Y, Ohno T, Hayashi A, Ide K, Ide S, Shoji M, Kitamoto T, Endo Y, Ogata H, Kubota Y, Mitsukawa N, Iwama A, Ouchi Y, Takayama N, Eto K, Fujii K, Takatani T, Shiohama T, Hamada H, Maezawa Y, Yokote K. Sawada D, et al. Among authors: ouchi y. Aging (Albany NY). 2023 Oct 3;15(19):9948-9964. doi: 10.18632/aging.205078. Epub 2023 Oct 3. Aging (Albany NY). 2023. PMID: 37793000 Free PMC article.
Metabolomic analysis of serum samples from a clinical study on ipragliflozin and metformin treatment in Japanese patients with type 2 diabetes: Exploring human metabolites associated with visceral fat reduction.
Tsukagoshi-Yamaguchi A, Koshizaka M, Ishibashi R, Ishikawa K, Ishikawa T, Shoji M, Ide S, Ide K, Baba Y, Terayama R, Hattori A, Takemoto M, Ouchi Y, Maezawa Y, Yokote K; PRIME-V study group. Tsukagoshi-Yamaguchi A, et al. Among authors: ouchi y. Pharmacotherapy. 2023 Dec;43(12):1317-1326. doi: 10.1002/phar.2884. Epub 2023 Oct 12. Pharmacotherapy. 2023. PMID: 37772313 Clinical Trial.
Retrotransposons in Werner syndrome-derived macrophages trigger type I interferon-dependent inflammation in an atherosclerosis model.
Paul SK, Oshima M, Patil A, Sone M, Kato H, Maezawa Y, Kaneko H, Fukuyo M, Rahmutulla B, Ouchi Y, Tsujimura K, Nakanishi M, Kaneda A, Iwama A, Yokote K, Eto K, Takayama N. Paul SK, et al. Among authors: ouchi y. Nat Commun. 2024 Jun 10;15(1):4772. doi: 10.1038/s41467-024-48663-w. Nat Commun. 2024. PMID: 38858384 Free PMC article.
FOXM1 delays senescence and extends lifespan.
Ouchi Y, Sahu SK, Izpisua Belmonte JC. Ouchi Y, et al. Nat Aging. 2022 May;2(5):373-374. doi: 10.1038/s43587-022-00222-y. Nat Aging. 2022. PMID: 37118068 No abstract available.
Transgenerational inheritance of acquired epigenetic signatures at CpG islands in mice.
Takahashi Y, Morales Valencia M, Yu Y, Ouchi Y, Takahashi K, Shokhirev MN, Lande K, Williams AE, Fresia C, Kurita M, Hishida T, Shojima K, Hatanaka F, Nuñez-Delicado E, Esteban CR, Izpisua Belmonte JC. Takahashi Y, et al. Among authors: ouchi y. Cell. 2023 Feb 16;186(4):715-731.e19. doi: 10.1016/j.cell.2022.12.047. Epub 2023 Feb 7. Cell. 2023. PMID: 36754048 Free article.
Intervention with metabolites emulating endogenous cell transitions accelerates muscle regeneration in young and aged mice.
Hernandez-Benitez R, Wang C, Shi L, Ouchi Y, Zhong C, Hishida T, Liao HK, Magill EA, Memczak S, Soligalla RD, Fresia C, Hatanaka F, Lamas V, Guillen I, Sahu S, Yamamoto M, Shao Y, Aguirre-Vazquez A, Nuñez Delicado E, Guillen P, Rodriguez Esteban C, Qu J, Reddy P, Horvath S, Liu GH, Magistretti P, Izpisua Belmonte JC. Hernandez-Benitez R, et al. Among authors: ouchi y. Cell Rep Med. 2024 Mar 19;5(3):101449. doi: 10.1016/j.xcrm.2024.101449. Cell Rep Med. 2024. PMID: 38508141 Free PMC article.
CHAMP1 premature termination codon mutations found in individuals with intellectual disability cause a homologous recombination defect through haploinsufficiency.
Yoshizaki Y, Ouchi Y, Kurniawan D, Yumoto E, Yoneyama Y, Rizqullah FR, Sato H, Sarholz MH, Natsume T, Kanemaki MT, Ikeda M, Ui A, Iemura K, Tanaka K. Yoshizaki Y, et al. Among authors: ouchi y. Sci Rep. 2024 Dec 30;14(1):31904. doi: 10.1038/s41598-024-83435-y. Sci Rep. 2024. PMID: 39738383 Free PMC article.
877 results