Mielke LA - Search Results

1

TCF-1 limits intraepithelial lymphocyte antitumor immunity in colorectal carcinoma.

Yakou MH, Ghilas S, Tran K, Liao Y, Afshar-Sterle S, Kumari A, Schmid K, Dijkstra C, Inguanti C, Ostrouska S, Wilcox J, Smith M, Parathan P, Allam A, Xue HH, Belz GT, Mariadason JM, Behren A, Drummond GR, Ruscher R, Williams DS, Pal B, Shi W, Ernst M, Raghu D, Mielke LA. Yakou MH, et al. Among authors: mielke la. Sci Immunol. 2023 Oct 13;8(88):eadf2163. doi: 10.1126/sciimmunol.adf2163. Epub 2023 Oct 6. Sci Immunol. 2023. PMID: 37801516

2

The comparative roles of suppressor of cytokine signaling-1 and -3 in the inhibition and desensitization of cytokine signaling.

Wormald S, Zhang JG, Krebs DL, Mielke LA, Silver J, Alexander WS, Speed TP, Nicola NA, Hilton DJ. Wormald S, et al. Among authors: mielke la. J Biol Chem. 2006 Apr 21;281(16):11135-43. doi: 10.1074/jbc.M509595200. Epub 2006 Feb 10. J Biol Chem. 2006. PMID: 16473883 Free article.

3

A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia.

Majewski IJ, Metcalf D, Mielke LA, Krebs DL, Ellis S, Carpinelli MR, Mifsud S, Di Rago L, Corbin J, Nicola NA, Hilton DJ, Alexander WS. Majewski IJ, et al. Among authors: mielke la. Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14146-51. doi: 10.1073/pnas.0606439103. Epub 2006 Sep 11. Proc Natl Acad Sci U S A. 2006. PMID: 16966598 Free PMC article.

4

Ablation of tumor progression locus 2 promotes a type 2 Th cell response in Ovalbumin-immunized mice.

Watford WT, Wang CC, Tsatsanis C, Mielke LA, Eliopoulos AG, Daskalakis C, Charles N, Odom S, Rivera J, O'Shea J, Tsichlis PN. Watford WT, et al. Among authors: mielke la. J Immunol. 2010 Jan 1;184(1):105-13. doi: 10.4049/jimmunol.0803730. Epub 2009 Dec 2. J Immunol. 2010. PMID: 19955521 Free PMC article.

5

Regulation of interleukin-1beta by interferon-gamma is species specific, limited by suppressor of cytokine signalling 1 and influences interleukin-17 production.

Masters SL, Mielke LA, Cornish AL, Sutton CE, O'Donnell J, Cengia LH, Roberts AW, Wicks IP, Mills KH, Croker BA. Masters SL, et al. Among authors: mielke la. EMBO Rep. 2010 Aug;11(8):640-6. doi: 10.1038/embor.2010.93. Epub 2010 Jul 2. EMBO Rep. 2010. PMID: 20596075 Free PMC article.

6

The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability.

Babon JJ, McManus EJ, Yao S, DeSouza DP, Mielke LA, Sprigg NS, Willson TA, Hilton DJ, Nicola NA, Baca M, Nicholson SE, Norton RS. Babon JJ, et al. Among authors: mielke la. Mol Cell. 2006 Apr 21;22(2):205-16. doi: 10.1016/j.molcel.2006.03.024. Mol Cell. 2006. PMID: 16630890 Free article.

7

Tumor progression locus 2 (Map3k8) is critical for host defense against Listeria monocytogenes and IL-1 beta production.

Mielke LA, Elkins KL, Wei L, Starr R, Tsichlis PN, O'Shea JJ, Watford WT. Mielke LA, et al. J Immunol. 2009 Dec 15;183(12):7984-93. doi: 10.4049/jimmunol.0901336. J Immunol. 2009. PMID: 19933865 Free PMC article.

8

Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii.

Watford WT, Hissong BD, Durant LR, Yamane H, Muul LM, Kanno Y, Tato CM, Ramos HL, Berger AE, Mielke L, Pesu M, Solomon B, Frucht DM, Paul WE, Sher A, Jankovic D, Tsichlis PN, O'Shea JJ. Watford WT, et al. J Exp Med. 2008 Nov 24;205(12):2803-12. doi: 10.1084/jem.20081461. Epub 2008 Nov 10. J Exp Med. 2008. PMID: 19001140 Free PMC article.

9

Socs3 maintains the specificity of biological responses to cytokine signals during granulocyte and macrophage differentiation.

Croker BA, Mielke LA, Wormald S, Metcalf D, Kiu H, Alexander WS, Hilton DJ, Roberts AW. Croker BA, et al. Among authors: mielke la. Exp Hematol. 2008 Jul;36(7):786-98. doi: 10.1016/j.exphem.2008.02.008. Epub 2008 Apr 8. Exp Hematol. 2008. PMID: 18400361 Free PMC article.

10

Development of hydrocephalus in mice lacking SOCS7.

Krebs DL, Metcalf D, Merson TD, Voss AK, Thomas T, Zhang JG, Rakar S, O'bryan MK, Willson TA, Viney EM, Mielke LA, Nicola NA, Hilton DJ, Alexander WS. Krebs DL, et al. Among authors: mielke la. Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15446-51. doi: 10.1073/pnas.0406870101. Epub 2004 Oct 19. Proc Natl Acad Sci U S A. 2004. PMID: 15494444 Free PMC article.

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