Im SC - Search Results

1

Bacterial expression, purification, and reconstitution of human steroid 5α-reductases in phospholipid liposomes and nanodiscs.

Im SC, Valentín-Goyco J, Peng HM, Auchus RJ. Im SC, et al. Methods Enzymol. 2023;689:263-276. doi: 10.1016/bs.mie.2023.05.005. Epub 2023 May 30. Methods Enzymol. 2023. PMID: 37802573 Free PMC article.

2

Cytochrome b5 Activates the 17,20-Lyase Activity of Human Cytochrome P450 17A1 by Increasing the Coupling of NADPH Consumption to Androgen Production.

Peng HM, Im SC, Pearl NM, Turcu AF, Rege J, Waskell L, Auchus RJ. Peng HM, et al. Among authors: im sc. Biochemistry. 2016 Aug 9;55(31):4356-65. doi: 10.1021/acs.biochem.6b00532. Epub 2016 Jul 29. Biochemistry. 2016. PMID: 27426448 Free PMC article.

3

Expression in Escherichia Coli, Purification, and Functional Reconstitution of Human Steroid 5α-Reductases.

Peng HM, Valentín-Goyco J, Im SC, Han B, Liu J, Qiao J, Auchus RJ. Peng HM, et al. Among authors: im sc. Endocrinology. 2020 Aug 1;161(8):bqaa117. doi: 10.1210/endocr/bqaa117. Endocrinology. 2020. PMID: 32716491 Free PMC article.

4

Non-Ionic Inulin-Based Polymer Nanodiscs Enable Functional Reconstitution of a Redox Complex Composed of Oppositely Charged CYP450 and CPR in a Lipid Bilayer Membrane.

Krishnarjuna B, Im SC, Ravula T, Marte J, Auchus RJ, Ramamoorthy A. Krishnarjuna B, et al. Among authors: im sc. Anal Chem. 2022 Aug 30;94(34):11908-11915. doi: 10.1021/acs.analchem.2c02489. Epub 2022 Aug 17. Anal Chem. 2022. PMID: 35977417 Free PMC article.

5

Influence of cholesterol on kinetic parameters for human aromatase (P450 19A1) in phospholipid nanodiscs.

Sumangala N, Im SC, Valentín-Goyco J, Auchus RJ. Sumangala N, et al. Among authors: im sc. J Inorg Biochem. 2023 Oct;247:112340. doi: 10.1016/j.jinorgbio.2023.112340. Epub 2023 Jul 24. J Inorg Biochem. 2023. PMID: 37544101 Free PMC article.

6

Characterization of nanodisc-forming peptides for membrane protein studies.

Krishnarjuna B, Sharma G, Im SC, Auchus R, Anantharamaiah GM, Ramamoorthy A. Krishnarjuna B, et al. Among authors: im sc. J Colloid Interface Sci. 2024 Jan;653(Pt B):1402-1414. doi: 10.1016/j.jcis.2023.09.162. Epub 2023 Sep 29. J Colloid Interface Sci. 2024. PMID: 37801850 Free PMC article.

7

Kinetics of Intermediate Release Enhances P450 11B2-Catalyzed Aldosterone Synthesis.

Valentín-Goyco J, Im SC, Auchus RJ. Valentín-Goyco J, et al. Among authors: im sc. Biochemistry. 2024 Apr 16;63(8):1026-1037. doi: 10.1021/acs.biochem.3c00725. Epub 2024 Apr 2. Biochemistry. 2024. PMID: 38564530

8

Reconstitution of the Cytb5-CytP450 Complex in Nanodiscs for Structural Studies using NMR Spectroscopy.

Zhang M, Huang R, Ackermann R, Im SC, Waskell L, Schwendeman A, Ramamoorthy A. Zhang M, et al. Among authors: im sc. Angew Chem Int Ed Engl. 2016 Mar 24;55(14):4497-9. doi: 10.1002/anie.201600073. Epub 2016 Feb 29. Angew Chem Int Ed Engl. 2016. PMID: 26924779

9

Effect of polymer charge on functional reconstitution of membrane proteins in polymer nanodiscs.

Ravula T , Hardin NZ , Bai J , Im SC , Waskell L , Ramamoorthy A . Ravula T , et al. Among authors: im sc. Chem Commun (Camb). 2018 Aug 23;54(69):9615-9618. doi: 10.1039/c8cc04184a. Chem Commun (Camb). 2018. PMID: 30094448 Free PMC article.

10

Expression, purification, and functional reconstitution of ¹⁹F-labeled cytochrome b5 in peptide nanodiscs for NMR studies.

Bai J, Wang J, Ravula T, Im SC, Anantharamaiah GM, Waskell L, Ramamoorthy A. Bai J, et al. Among authors: im sc. Biochim Biophys Acta Biomembr. 2020 May 1;1862(5):183194. doi: 10.1016/j.bbamem.2020.183194. Epub 2020 Jan 15. Biochim Biophys Acta Biomembr. 2020. PMID: 31953231 Free PMC article.

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