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The malate shuttle detoxifies ammonia in exhausted T cells by producing 2-ketoglutarate.
Weisshaar N, Ma S, Ming Y, Madi A, Mieg A, Hering M, Zettl F, Mohr K, Ten Bosch N, Stichling D, Buettner M, Poschet G, Klinke G, Schulz M, Kunze-Rohrbach N, Kerber C, Klein IM, Wu J, Wang X, Cui G. Weisshaar N, et al. Among authors: klein im. Nat Immunol. 2023 Nov;24(11):1921-1932. doi: 10.1038/s41590-023-01636-5. Epub 2023 Oct 9. Nat Immunol. 2023. PMID: 37813964 Free PMC article.
MicroRNAs modulate SARS-CoV-2 infection of primary human hepatocytes by regulating the entry factors ACE2 and TMPRSS2.
Khanal R, Heinen N, Bogomolova A, Meister TL, Herrmann ST, Westhoven S, Nocke MK, Todt D, Jockenhövel F, Klein IM, Hartmann L, Vondran FWR, Steinmann E, Zimmer G, Ott M, Brown RJP, Sharma AD, Pfaender S. Khanal R, et al. Among authors: klein im. Liver Int. 2024 Nov;44(11):2983-2995. doi: 10.1111/liv.16079. Epub 2024 Aug 22. Liver Int. 2024. PMID: 39175256 Free article.
First report from the German COVID-19 autopsy registry.
von Stillfried S, Bülow RD, Röhrig R, Boor P; German Registry of COVID-19 Autopsies (DeRegCOVID), DeRegCOVID Collaborators. von Stillfried S, et al. Lancet Reg Health Eur. 2022 Feb 18;15:100330. doi: 10.1016/j.lanepe.2022.100330. eCollection 2022 Apr. Lancet Reg Health Eur. 2022. PMID: 35531493 Free PMC article.
Oncology enters the informatics era.
Klein IM. Klein IM. Am J Manag Care. 2012 Dec;18(5 Spec No.):SP218-21. Am J Manag Care. 2012. PMID: 23301710 Free article. Review. No abstract available.
13 results