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Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.
Tan SM, Li F, Rajendran P, Kumar AP, Hui KM, Sethi G. Tan SM, et al. Among authors: hui km. J Pharmacol Exp Ther. 2010 Jul;334(1):285-93. doi: 10.1124/jpet.110.165498. Epub 2010 Apr 8. J Pharmacol Exp Ther. 2010. PMID: 20378717
Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma.
Subramaniam A, Shanmugam MK, Perumal E, Li F, Nachiyappan A, Dai X, Swamy SN, Ahn KS, Kumar AP, Tan BK, Hui KM, Sethi G. Subramaniam A, et al. Among authors: hui km. Biochim Biophys Acta. 2013 Jan;1835(1):46-60. doi: 10.1016/j.bbcan.2012.10.002. Epub 2012 Oct 26. Biochim Biophys Acta. 2013. PMID: 23103770 Review.
An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins.
Subramaniam A, Loo SY, Rajendran P, Manu KA, Perumal E, Li F, Shanmugam MK, Siveen KS, Park JI, Ahn KS, Hui KM, Kumar AP, Sethi G. Subramaniam A, et al. Among authors: hui km. Apoptosis. 2013 Oct;18(10):1175-87. doi: 10.1007/s10495-013-0851-5. Apoptosis. 2013. PMID: 23700228
213 results