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Page 1
Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators.
Kühnisch J, Theisen S, Dartsch J, Fritsche-Guenther R, Kirchner M, Obermayer B, Bauer A, Kahlert AK, Rothe M, Beule D, Heuser A, Mertins P, Kirwan JA, Berndt N, MacRae CA, Hubner N, Klaassen S. Kühnisch J, et al. Among authors: dartsch j. Cardiovasc Res. 2024 Feb 17;119(18):2902-2916. doi: 10.1093/cvr/cvad154. Cardiovasc Res. 2024. PMID: 37842925 Free PMC article.
Pathogenic Variants in Cardiomyopathy Disorder Genes Underlie Pediatric Myocarditis-Further Impact of Heterozygous Immune Disorder Gene Variants?
Seidel F, Laser KT, Klingel K, Dartsch J, Theisen S, Pickardt T, Holtgrewe M, Gärtner A, Berger F, Beule D, Milting H, Schubert S, Klaassen S, Kühnisch J. Seidel F, et al. Among authors: dartsch j. J Cardiovasc Dev Dis. 2022 Jul 5;9(7):216. doi: 10.3390/jcdd9070216. J Cardiovasc Dev Dis. 2022. PMID: 35877578 Free PMC article.
Transmission ratio distortion of mutations in the master regulator of centriole biogenesis PLK4.
Neitzel H, Varon R, Chughtai S, Dartsch J, Dutrannoy-Tönsing V, Nürnberg P, Nürnberg G, Schweiger M, Digweed M, Hildebrand G, Hackmann K, Holtgrewe M, Sarioglu N, Schulze B, Horn D, Sperling K. Neitzel H, et al. Among authors: dartsch j. Hum Genet. 2022 Nov;141(11):1785-1794. doi: 10.1007/s00439-022-02461-w. Epub 2022 May 10. Hum Genet. 2022. PMID: 35536377 Free PMC article.
Reduced Systolic Function and Not Genetic Variants Determine Outcome in Pediatric and Adult Left Ventricular Noncompaction Cardiomyopathy.
Schultze-Berndt A, Kühnisch J, Herbst C, Seidel F, Al-Wakeel-Marquard N, Dartsch J, Theisen S, Knirsch W, Jenni R, Greutmann M, Oechslin E, Berger F, Klaassen S. Schultze-Berndt A, et al. Among authors: dartsch j. Front Pediatr. 2021 Sep 3;9:722926. doi: 10.3389/fped.2021.722926. eCollection 2021. Front Pediatr. 2021. PMID: 34540771 Free PMC article.
Pathogenic Variants Associated With Dilated Cardiomyopathy Predict Outcome in Pediatric Myocarditis.
Seidel F, Holtgrewe M, Al-Wakeel-Marquard N, Opgen-Rhein B, Dartsch J, Herbst C, Beule D, Pickardt T, Klingel K, Messroghli D, Berger F, Schubert S, Kühnisch J, Klaassen S. Seidel F, et al. Among authors: dartsch j. Circ Genom Precis Med. 2021 Aug;14(4):e003250. doi: 10.1161/CIRCGEN.120.003250. Epub 2021 Jul 2. Circ Genom Precis Med. 2021. PMID: 34213952 Free PMC article. Clinical Trial.
Targeted panel sequencing in pediatric primary cardiomyopathy supports a critical role of TNNI3.
Kühnisch J, Herbst C, Al-Wakeel-Marquard N, Dartsch J, Holtgrewe M, Baban A, Mearini G, Hardt J, Kolokotronis K, Gerull B, Carrier L, Beule D, Schubert S, Messroghli D, Degener F, Berger F, Klaassen S. Kühnisch J, et al. Among authors: dartsch j. Clin Genet. 2019 Dec;96(6):549-559. doi: 10.1111/cge.13645. Epub 2019 Oct 22. Clin Genet. 2019. PMID: 31568572
RIKADA Study Reveals Risk Factors in Pediatric Primary Cardiomyopathy.
Al-Wakeel-Marquard N, Degener F, Herbst C, Kühnisch J, Dartsch J, Schmitt B, Kuehne T, Messroghli D, Berger F, Klaassen S. Al-Wakeel-Marquard N, et al. Among authors: dartsch j. J Am Heart Assoc. 2019 Aug 6;8(15):e012531. doi: 10.1161/JAHA.119.012531. Epub 2019 Jul 23. J Am Heart Assoc. 2019. PMID: 31333075 Free PMC article.