Koren I - Search Results

1

Molecular basis for C-degron recognition by CRL2^APPBP2 ubiquitin ligase.

Zhao S, Olmayev-Yaakobov D, Ru W, Li S, Chen X, Zhang J, Yao X, Koren I, Zhang K, Xu C. Zhao S, et al. Among authors: koren i. Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2308870120. doi: 10.1073/pnas.2308870120. Epub 2023 Oct 16. Proc Natl Acad Sci U S A. 2023. PMID: 37844242 Free PMC article.

2

DAP1, a novel substrate of mTOR, negatively regulates autophagy.

Koren I, Reem E, Kimchi A. Koren I, et al. Curr Biol. 2010 Jun 22;20(12):1093-8. doi: 10.1016/j.cub.2010.04.041. Epub 2010 May 27. Curr Biol. 2010. PMID: 20537536 Free article.

3

The Eukaryotic Proteome Is Shaped by E3 Ubiquitin Ligases Targeting C-Terminal Degrons.

Koren I, Timms RT, Kula T, Xu Q, Li MZ, Elledge SJ. Koren I, et al. Cell. 2018 Jun 14;173(7):1622-1635.e14. doi: 10.1016/j.cell.2018.04.028. Epub 2018 May 17. Cell. 2018. PMID: 29779948 Free PMC article.

4

Cell biology. Promoting tumorigenesis by suppressing autophagy.

Koren I, Kimchi A. Koren I, et al. Science. 2012 Nov 16;338(6109):889-90. doi: 10.1126/science.1230577. Science. 2012. PMID: 23161981 No abstract available.

5

Molecular basis for arginine C-terminal degron recognition by Cul2^FEM1 E3 ligase.

Chen X, Liao S, Makaros Y, Guo Q, Zhu Z, Krizelman R, Dahan K, Tu X, Yao X, Koren I, Xu C. Chen X, et al. Among authors: koren i. Nat Chem Biol. 2021 Mar;17(3):254-262. doi: 10.1038/s41589-020-00704-3. Epub 2021 Jan 4. Nat Chem Biol. 2021. PMID: 33398168

6

Ubiquitin-independent proteasomal degradation driven by C-degron pathways.

Makaros Y, Raiff A, Timms RT, Wagh AR, Gueta MI, Bekturova A, Guez-Haddad J, Brodsky S, Opatowsky Y, Glickman MH, Elledge SJ, Koren I. Makaros Y, et al. Among authors: koren i. Mol Cell. 2023 Jun 1;83(11):1921-1935.e7. doi: 10.1016/j.molcel.2023.04.023. Epub 2023 May 17. Mol Cell. 2023. PMID: 37201526 Free PMC article.

7

Mechanism of Ψ-Pro/C-degron recognition by the CRL2^FEM1B ubiquitin ligase.

Chen X, Raiff A, Li S, Guo Q, Zhang J, Zhou H, Timms RT, Yao X, Elledge SJ, Koren I, Zhang K, Xu C. Chen X, et al. Among authors: koren i. Nat Commun. 2024 Apr 26;15(1):3558. doi: 10.1038/s41467-024-47890-5. Nat Commun. 2024. PMID: 38670995 Free PMC article.

8

Dipeptidyl peptidases and E3 ligases of N-degron pathways cooperate to regulate protein stability.

Shimshon A, Dahan K, Israel-Gueta M, Olmayev-Yaakobov D, Timms RT, Bekturova A, Makaros Y, Elledge SJ, Koren I. Shimshon A, et al. Among authors: koren i. J Cell Biol. 2024 Aug 5;223(8):e202311035. doi: 10.1083/jcb.202311035. Epub 2024 Jun 14. J Cell Biol. 2024. PMID: 38874443 Free PMC article.

9

Tying up loose ends: the N-degron and C-degron pathways of protein degradation.

Timms RT, Koren I. Timms RT, et al. Among authors: koren i. Biochem Soc Trans. 2020 Aug 28;48(4):1557-1567. doi: 10.1042/BST20191094. Biochem Soc Trans. 2020. PMID: 32627813 Free PMC article. Review.

10

Defining E3 ligase-substrate relationships through multiplex CRISPR screening.

Timms RT, Mena EL, Leng Y, Li MZ, Tchasovnikarova IA, Koren I, Elledge SJ. Timms RT, et al. Among authors: koren i. Nat Cell Biol. 2023 Oct;25(10):1535-1545. doi: 10.1038/s41556-023-01229-2. Epub 2023 Sep 21. Nat Cell Biol. 2023. PMID: 37735597 Free PMC article.

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