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Testing the PEST hypothesis using relevant Rett mutations in MeCP2 E1 and E2 isoforms.
Kalani L, Kim BH, de Chavez AR, Roemer A, Mikhailov A, Merritt JK, Good KV, Chow RL, Delaney KR, Hendzel MJ, Zhou Z, Neul JL, Vincent JB, Ausió J. Kalani L, et al. Among authors: ausio j. Hum Mol Genet. 2024 Nov 5;33(21):1833-1845. doi: 10.1093/hmg/ddae119. Hum Mol Genet. 2024. PMID: 39137370 Free PMC article.
Extending MeCP2 interactome: canonical nucleosomal histones interact with MeCP2.
Ortega-Alarcon D, Claveria-Gimeno R, Vega S, Kalani L, Jorge-Torres OC, Esteller M, Ausio J, Abian O, Velazquez-Campoy A. Ortega-Alarcon D, et al. Among authors: ausio j. Nucleic Acids Res. 2024 Apr 24;52(7):3636-3653. doi: 10.1093/nar/gkae051. Nucleic Acids Res. 2024. PMID: 38321951 Free PMC article.
A complex interplay between H2A.Z and HP1 isoforms regulates pericentric heterochromatin.
González J, Bosch-Presegué L, Marazuela-Duque A, Guitart-Solanes A, Espinosa-Alcantud M, Fernandez AF, Brown JP, Ausió J, Vazquez BN, Singh PB, Fraga MF, Vaquero A. González J, et al. Among authors: ausio j. Front Cell Dev Biol. 2023 Nov 9;11:1293122. doi: 10.3389/fcell.2023.1293122. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 38020886 Free PMC article.
Epigenetic modulation via the C-terminal tail of H2A.Z.
Imre L, Nánási P Jr, Benhamza I, Enyedi KN, Mocsár G, Bosire R, Hegedüs É, Niaki EF, Csóti Á, Darula Z, Csősz É, Póliska S, Scholtz B, Mező G, Bacsó Z, Timmers HTM, Kusakabe M, Balázs M, Vámosi G, Ausio J, Cheung P, Tóth K, Tremethick D, Harata M, Szabó G. Imre L, et al. Among authors: ausio j. Nat Commun. 2024 Oct 24;15(1):9171. doi: 10.1038/s41467-024-53514-9. Nat Commun. 2024. PMID: 39448645 Free PMC article.
The protamines of the noble false widow spider Steatoda nobilis provide an example of liquid-liquid phase separation chromatin transitions during spermiogenesis.
Leyden MR, Michalik P, Baruffaldi L, Mahmood S, Kalani L, Hunt DF, Eirin-Lopez JM, Andrade MCB, Shabanowitz J, Ausió J. Leyden MR, et al. Among authors: ausio j. bioRxiv [Preprint]. 2024 Jun 5:2024.06.04.597381. doi: 10.1101/2024.06.04.597381. bioRxiv. 2024. Update in: Development. 2024 Nov 15;151(22):dev203134. doi: 10.1242/dev.203134 PMID: 38895387 Free PMC article. Updated. Preprint.
256 results