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Late-life exercise mitigates skeletal muscle epigenetic aging.
Murach KA, Dimet-Wiley AL, Wen Y, Brightwell CR, Latham CM, Dungan CM, Fry CS, Watowich SJ. Murach KA, et al. Among authors: wen y. Aging Cell. 2022 Jan;21(1):e13527. doi: 10.1111/acel.13527. Epub 2021 Dec 21. Aging Cell. 2022. PMID: 34932867 Free PMC article.
Senolytic treatment rescues blunted muscle hypertrophy in old mice.
Dungan CM, Figueiredo VC, Wen Y, VonLehmden GL, Zdunek CJ, Thomas NT, Mobley CB, Murach KA, Brightwell CR, Long DE, Fry CS, Kern PA, McCarthy JJ, Peterson CA. Dungan CM, et al. Among authors: wen y. Geroscience. 2022 Aug;44(4):1925-1940. doi: 10.1007/s11357-022-00542-2. Epub 2022 Mar 24. Geroscience. 2022. PMID: 35325353 Free PMC article.
A molecular signature defining exercise adaptation with ageing and in vivo partial reprogramming in skeletal muscle.
Jones RG 3rd, Dimet-Wiley A, Haghani A, da Silva FM, Brightwell CR, Lim S, Khadgi S, Wen Y, Dungan CM, Brooke RT, Greene NP, Peterson CA, McCarthy JJ, Horvath S, Watowich SJ, Fry CS, Murach KA. Jones RG 3rd, et al. Among authors: wen y. J Physiol. 2023 Feb;601(4):763-782. doi: 10.1113/JP283836. Epub 2023 Jan 24. J Physiol. 2023. PMID: 36533424 Free PMC article.
Inhibition of p53-MDM2 binding reduces senescent cell abundance and improves the adaptive responses of skeletal muscle from aged mice.
Nolt GL, Keeble AR, Wen Y, Strong AC, Thomas NT, Valentino TR, Brightwell CR, Murach KA, Patrizia S, Weinstabl H, Gollner A, McCarthy JJ, Fry CS, Franti M, Filareto A, Peterson CA, Dungan CM. Nolt GL, et al. Among authors: wen y. Geroscience. 2024 Apr;46(2):2153-2176. doi: 10.1007/s11357-023-00976-2. Epub 2023 Oct 24. Geroscience. 2024. PMID: 37872294 Free PMC article.
Coordinated Regulation of Myonuclear DNA Methylation, mRNA, and miRNA Levels Associates With the Metabolic Response to Rapid Synergist Ablation-Induced Skeletal Muscle Hypertrophy in Female Mice.
Ismaeel A, Thomas NT, McCashland M, Vechetti IJ, Edman S, Lanner JT, Figueiredo VC, Fry CS, McCarthy JJ, Wen Y, Murach KA, von Walden F. Ismaeel A, et al. Among authors: wen y. Function (Oxf). 2023 Nov 6;5(1):zqad062. doi: 10.1093/function/zqad062. eCollection 2024. Function (Oxf). 2023. PMID: 38020067 Free PMC article.
9,628 results