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Page 1
Oligo-metastatic neoPlasms from the gastro-intestinal tract: iDentIfiCaTIon of cliNical and molecular drivers: the PREDICTION study.
Ottaiano A, De Luca A, Santorsola M, Scognamiglio G, Di Mauro A, Chiodini P, Lambiase M, Sacco A, Petrillo A, Granata V, Fusco R, Mercadante E, Martucci N, De Luca G, Rocca A, Celentano E, Crispo A, Di Gennaro P, Tatangelo F, Ferrara G, Izzo F, Belli A, Patrone R, Delrio P, Rega D, De Franciscis S, Muto P, Ravo V, Di Franco R, Borzillo V, Santagata S, Rea G, Castaldo D, Pace U, De Feo G, Scala S, Nasti G, Normanno N. Ottaiano A, et al. Among authors: scala s. BMC Cancer. 2023 Oct 19;23(1):1010. doi: 10.1186/s12885-023-11479-w. BMC Cancer. 2023. PMID: 37858132 Free PMC article.
Hepatocellular carcinoma (HCC) tumor microenvironment is more suppressive than colorectal cancer liver metastasis (CRLM) tumor microenvironment.
Santagata S, Rea G, Castaldo D, Napolitano M, Capiluongo A, D'Alterio C, Trotta AM, Ieranò C, Portella L, Di Maro S, Tatangelo F, Albino V, Guarino R, Cutolo C, Izzo F, Scala S. Santagata S, et al. Among authors: scala s. Hepatol Int. 2024 Apr;18(2):568-581. doi: 10.1007/s12072-023-10537-6. Epub 2023 May 4. Hepatol Int. 2024. PMID: 37142825 Free PMC article.
Comprehensive structural investigation of a potent and selective CXCR4 antagonist via crosslink modification.
Trotta AM, Mazzarella V, Roggia M, D'Aniello A, Del Bene A, Vetrei C, Di Maiolo G, Campagna E, Natale B, Rea G, Santagata S, D'Alterio C, Cutolo R, Mottola S, Merlino F, Benedetti R, Altucci L, Messere A, Cosconati S, Tomassi S, Scala S, Di Maro S. Trotta AM, et al. Among authors: scala s. Eur J Med Chem. 2024 Dec 5;279:116911. doi: 10.1016/j.ejmech.2024.116911. Epub 2024 Sep 25. Eur J Med Chem. 2024. PMID: 39348763
Disulfide bond replacement with non-reducible side chain to tail macrolactamization for the development of potent and selective CXCR4 peptide antagonists endowed with flanking binding sites.
Trotta AM, Tomassi S, Di Maiolo G, Ieranò C, Vetrei C, D'Alterio C, Merlino F, Messere A, D'Aniello A, Del Bene A, Mazzarella V, Roggia M, Natale B, Cutolo R, Campagna E, Mottola S, Russo R, Chambery A, Benedetti R, Altucci L, Cosconati S, Scala S, Di Maro S. Trotta AM, et al. Among authors: scala s. Eur J Med Chem. 2024 Oct 5;276:116669. doi: 10.1016/j.ejmech.2024.116669. Epub 2024 Jul 14. Eur J Med Chem. 2024. PMID: 39053189
Reduced G protein signaling despite impaired internalization and β-arrestin recruitment in patients carrying a CXCR4Leu317fsX3 mutation causing WHIM syndrome.
Kumar R, Milanesi S, Szpakowska M, Dotta L, Di Silvestre D, Trotta AM, Bello AM, Giacomelli M, Benedito M, Azevedo J, Pereira A, Cortesao E, Vacchini A, Castagna A, Pinelli M, Moratto D, Bonecchi R, Locati M, Scala S, Chevigné A, Borroni EM, Badolato R. Kumar R, et al. Among authors: scala s. JCI Insight. 2023 Mar 8;8(5):e145688. doi: 10.1172/jci.insight.145688. JCI Insight. 2023. PMID: 36883568 Free PMC article.
First Detection of Lactococcus petauri in Domestic Dogs in Italy.
Sciuto S, Esposito G, Pastorino P, Shahin K, Varello K, Trabunella E, Milanese G, Scala S, Prearo M, Acutis PL, Salerno A, Zoppi S, Colussi S. Sciuto S, et al. Among authors: scala s. Animals (Basel). 2024 Nov 14;14(22):3279. doi: 10.3390/ani14223279. Animals (Basel). 2024. PMID: 39595331 Free PMC article.
Long-term lineage commitment in haematopoietic stem cell gene therapy.
Calabria A, Spinozzi G, Cesana D, Buscaroli E, Benedicenti F, Pais G, Gazzo F, Scala S, Lidonnici MR, Scaramuzza S, Albertini A, Esposito S, Tucci F, Canarutto D, Omrani M, De Mattia F, Dionisio F, Giannelli S, Marktel S, Fumagalli F, Calbi V, Cenciarelli S, Ferrua F, Gentner B, Caravagna G, Ciceri F, Naldini L, Ferrari G, Aiuti A, Montini E. Calabria A, et al. Among authors: scala s. Nature. 2024 Dec;636(8041):162-171. doi: 10.1038/s41586-024-08250-x. Epub 2024 Oct 23. Nature. 2024. PMID: 39442556 Free PMC article.
260 results