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Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells.
Xue D, Narisu N, Taylor DL, Zhang M, Grenko C, Taylor HJ, Yan T, Tang X, Sinha N, Zhu J, Vandana JJ, Nok Chong AC, Lee A, Mansell EC, Swift AJ, Erdos MR, Zhong A, Bonnycastle LL, Zhou T, Chen S, Collins FS. Xue D, et al. Among authors: zhong a. Cell Metab. 2023 Nov 7;35(11):1897-1914.e11. doi: 10.1016/j.cmet.2023.09.013. Epub 2023 Oct 18. Cell Metab. 2023. PMID: 37858332 Free PMC article.
A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.
Han Y, Tan L, Zhou T, Yang L, Carrau L, Lacko LA, Saeed M, Zhu J, Zhao Z, Nilsson-Payant BE, Lira Neto FT, Cahir C, Giani AM, Chai JC, Li Y, Dong X, Moroziewicz D; NYSCF Global Stem Cell Array Team; Paull D, Zhang T, Koo S, Tan C, Danziger R, Ba Q, Feng L, Chen Z, Zhong A, Wise GJ, Xiang JZ, Wang H, Schwartz RE, tenOever BR, Noggle SA, Rice CM, Qi Q, Evans T, Chen S. Han Y, et al. Among authors: zhong a. Cell Stem Cell. 2022 Oct 6;29(10):1475-1490.e6. doi: 10.1016/j.stem.2022.09.008. Cell Stem Cell. 2022. PMID: 36206731 Free PMC article.
Functional interrogation of twenty type 2 diabetes-associated genes using isogenic hESC-derived β-like cells.
Xue D, Narisu N, Taylor DL, Zhang M, Grenko C, Taylor HJ, Yan T, Tang X, Sinha N, Zhu J, Vandana JJ, Chong ACN, Lee A, Mansell EC, Swift AJ, Erdos MR, Zhou T, Bonnycastle LL, Zhong A, Chen S, Collins FS. Xue D, et al. Among authors: zhong a. bioRxiv [Preprint]. 2023 May 8:2023.05.07.539774. doi: 10.1101/2023.05.07.539774. bioRxiv. 2023. Update in: Cell Metab. 2023 Nov 7;35(11):1897-1914.e11. doi: 10.1016/j.cmet.2023.09.013 PMID: 37214922 Free PMC article. Updated. Preprint.
Isogenic human trophectoderm cells demonstrate the role of NDUFA4 and associated variants in ZIKV infection.
Yang L, Han Y, Zhou T, Lacko LA, Saeed M, Tan C, Danziger R, Zhu J, Zhao Z, Cahir C, Giani AM, Li Y, Dong X, Moroziewicz D; NYSCF Global Stem Cell Array® Team; Paull D, Chen Z, Zhong A, Noggle SA, Rice CM, Qi Q, Evans T, Chen S. Yang L, et al. Among authors: zhong a. iScience. 2023 May 29;26(7):107001. doi: 10.1016/j.isci.2023.107001. eCollection 2023 Jul 21. iScience. 2023. PMID: 37534130 Free PMC article.
An integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D associated genes and regulatory signals.
Zhao Z, D'Oliveira Albanus R, Taylor H, Tang X, Han Y, Orchard P, Varshney A, Zhang T, Manickam N, Erdos M, Narisu N, Taylor L, Saavedra X, Zhong A, Li B, Zhou T, Naji A, Liu C, Collins F, Parker SC, Chen S. Zhao Z, et al. Among authors: zhong a. Res Sq [Preprint]. 2023 Oct 18:rs.3.rs-3343318. doi: 10.21203/rs.3.rs-3343318/v1. Res Sq. 2023. PMID: 37886586 Free PMC article. Preprint.
hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease.
Fan Y, Hackland J, Baggiolini A, Hung LY, Zhao H, Zumbo P, Oberst P, Minotti AP, Hergenreder E, Najjar S, Huang Z, Cruz NM, Zhong A, Sidharta M, Zhou T, de Stanchina E, Betel D, White RM, Gershon M, Margolis KG, Studer L. Fan Y, et al. Among authors: zhong a. Cell Stem Cell. 2023 Mar 2;30(3):264-282.e9. doi: 10.1016/j.stem.2023.02.003. Cell Stem Cell. 2023. PMID: 36868194 Free PMC article.
479 results