Lu Y - Search Results

1

The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity.

Stewart H, Lu Y, O'Keefe S, Valpadashi A, Cruz-Zaragoza LD, Michel HA, Nguyen SK, Carnell GW, Lukhovitskaya N, Milligan R, Adewusi Y, Jungreis I, Lulla V, Matthews DA, High S, Rehling P, Emmott E, Heeney JL, Davidson AD, Edgar JR, Smith GL, Firth AE. Stewart H, et al. Among authors: lu y. iScience. 2023 Sep 28;26(11):108080. doi: 10.1016/j.isci.2023.108080. eCollection 2023 Nov 17. iScience. 2023. PMID: 37860693 Free PMC article.

2

Vaccinia Virus Protein C6 Inhibits Type I IFN Signalling in the Nucleus and Binds to the Transactivation Domain of STAT2.

Stuart JH, Sumner RP, Lu Y, Snowden JS, Smith GL. Stuart JH, et al. Among authors: lu y. PLoS Pathog. 2016 Dec 1;12(12):e1005955. doi: 10.1371/journal.ppat.1005955. eCollection 2016 Dec. PLoS Pathog. 2016. PMID: 27907166 Free PMC article.

3

How Does Vaccinia Virus Interfere With Interferon?

Smith GL, Talbot-Cooper C, Lu Y. Smith GL, et al. Among authors: lu y. Adv Virus Res. 2018;100:355-378. doi: 10.1016/bs.aivir.2018.01.003. Epub 2018 Feb 16. Adv Virus Res. 2018. PMID: 29551142 Review.

4

Quantitative Temporal Proteomic Analysis of Vaccinia Virus Infection Reveals Regulation of Histone Deacetylases by an Interferon Antagonist.

Soday L, Lu Y, Albarnaz JD, Davies CTR, Antrobus R, Smith GL, Weekes MP. Soday L, et al. Among authors: lu y. Cell Rep. 2019 May 7;27(6):1920-1933.e7. doi: 10.1016/j.celrep.2019.04.042. Cell Rep. 2019. PMID: 31067474 Free PMC article.

5

DDX50 Is a Viral Restriction Factor That Enhances IRF3 Activation.

Pallett MA, Lu Y, Smith GL. Pallett MA, et al. Among authors: lu y. Viruses. 2022 Feb 3;14(2):316. doi: 10.3390/v14020316. Viruses. 2022. PMID: 35215908 Free PMC article.

6

Manipulation of innate immune signaling pathways by SARS-CoV-2 non-structural proteins.

Lu Y, Michel HA, Wang PH, Smith GL. Lu Y, et al. Front Microbiol. 2022 Nov 21;13:1027015. doi: 10.3389/fmicb.2022.1027015. eCollection 2022. Front Microbiol. 2022. PMID: 36478862 Free PMC article.

7

TRIM5α restricts poxviruses and is antagonized by CypA and the viral protein C6.

Zhao Y, Lu Y, Richardson S, Sreekumar M, Albarnaz JD, Smith GL. Zhao Y, et al. Among authors: lu y. Nature. 2023 Aug;620(7975):873-880. doi: 10.1038/s41586-023-06401-0. Epub 2023 Aug 9. Nature. 2023. PMID: 37558876 Free PMC article.

8

Filamin B restricts vaccinia virus spread and is targeted by vaccinia virus protein C4.

Georgana I, Scutts SR, Gao C, Lu Y, Torres AA, Ren H, Emmott E, Men J, Oei K, Smith GL. Georgana I, et al. Among authors: lu y. J Virol. 2024 Mar 19;98(3):e0148523. doi: 10.1128/jvi.01485-23. Epub 2024 Feb 27. J Virol. 2024. PMID: 38412044 Free PMC article.

9

HDAC5 enhances IRF3 activation and is targeted for degradation by protein C6 from orthopoxviruses including Monkeypox virus and Variola virus.

Lu Y, Zhao Y, Gao C, Suresh S, Men J, Sawyers A, Smith GL. Lu Y, et al. Cell Rep. 2024 Mar 26;43(3):113788. doi: 10.1016/j.celrep.2024.113788. Epub 2024 Mar 10. Cell Rep. 2024. PMID: 38461415 Free PMC article.

10

The nuclear localization signal of monkeypox virus protein P2 orthologue is critical for inhibition of IRF3-mediated innate immunity.

Jiao P, Ma J, Zhao Y, Jia X, Zhang H, Fan W, Jia X, Bai X, Zhao Y, Lu Y, Zhang H, Guo J, Pang G, Zhang K, Fang M, Li M, Liu W, Smith GL, Sun L. Jiao P, et al. Among authors: lu y. Emerg Microbes Infect. 2024 Dec;13(1):2372344. doi: 10.1080/22221751.2024.2372344. Epub 2024 Jul 6. Emerg Microbes Infect. 2024. PMID: 38916407 Free PMC article.

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