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Page 1
In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases.
Kerzel T, Giacca G, Beretta S, Bresesti C, Notaro M, Scotti GM, Balestrieri C, Canu T, Redegalli M, Pedica F, Genua M, Ostuni R, Kajaste-Rudnitski A, Oshima M, Tonon G, Merelli I, Aldrighetti L, Dellabona P, Coltella N, Doglioni C, Rancoita PMV, Sanvito F, Naldini L, Squadrito ML. Kerzel T, et al. Cancer Cell. 2023 Nov 13;41(11):1892-1910.e10. doi: 10.1016/j.ccell.2023.09.014. Epub 2023 Oct 19. Cancer Cell. 2023. PMID: 37863068 Free article.
MNK2 governs the macrophage antiinflammatory phenotype.
Bartish M, Tong D, Pan Y, Wallerius M, Liu H, Ristau J, de Souza Ferreira S, Wallmann T, van Hoef V, Masvidal L, Kerzel T, Joly AL, Goncalves C, Preston SEJ, Ebrahimian T, Seitz C, Bergh J, Pietras K, Lehoux S, Naldini L, Andersson J, Squadrito ML, Del Rincón SV, Larsson O, Rolny C. Bartish M, et al. Among authors: kerzel t. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27556-27565. doi: 10.1073/pnas.1920377117. Epub 2020 Oct 19. Proc Natl Acad Sci U S A. 2020. PMID: 33077599 Free PMC article.
Laboratory-Scale Lentiviral Vector Production and Purification for Enhanced Ex Vivo and In Vivo Genetic Engineering.
Soldi M, Sergi Sergi L, Unali G, Kerzel T, Cuccovillo I, Capasso P, Annoni A, Biffi M, Rancoita PMV, Cantore A, Lombardo A, Naldini L, Squadrito ML, Kajaste-Rudnitski A. Soldi M, et al. Among authors: kerzel t. Mol Ther Methods Clin Dev. 2020 Oct 20;19:411-425. doi: 10.1016/j.omtm.2020.10.009. eCollection 2020 Dec 11. Mol Ther Methods Clin Dev. 2020. PMID: 33294490 Free PMC article.
VEGF-C-expressing TAMs rewire the metastatic fate of breast cancer cells.
Banerjee K, Kerzel T, Bekkhus T, de Souza Ferreira S, Wallmann T, Wallerius M, Landwehr LS, Agardy DA, Schauer N, Malmerfeldt A, Bergh J, Bartish M, Hartman J, Östman A, Squadrito ML, Rolny C. Banerjee K, et al. Among authors: kerzel t. Cell Rep. 2023 Dec 26;42(12):113507. doi: 10.1016/j.celrep.2023.113507. Epub 2023 Dec 1. Cell Rep. 2023. PMID: 38041815 Free article.
GluA4-Targeted AAV Vectors Deliver Genes Selectively to Interneurons while Relying on the AAV Receptor for Entry.
Hartmann J, Thalheimer FB, Höpfner F, Kerzel T, Khodosevich K, García-González D, Monyer H, Diester I, Büning H, Carette JE, Fries P, Buchholz CJ. Hartmann J, et al. Among authors: kerzel t. Mol Ther Methods Clin Dev. 2019 Jul 23;14:252-260. doi: 10.1016/j.omtm.2019.07.004. eCollection 2019 Sep 13. Mol Ther Methods Clin Dev. 2019. PMID: 31463334 Free PMC article.