The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm.
Hamdorf M, Imhof T, Bailey-Elkin B, Betz J, Theobald SJ, Simonis A, Di Cristanziano V, Gieselmann L, Dewald F, Lehmann C, Augustin M, Klein F, Alejandre Alcazar MA, Rongisch R, Fabri M, Rybniker J, Goebel H, Stetefeld J, Brachvogel B, Cursiefen C, Koch M, Bock F.
Hamdorf M, et al. Among authors: fabri m.
J Mol Cell Biol. 2024 Apr 4;15(10):mjad062. doi: 10.1093/jmcb/mjad062.
J Mol Cell Biol. 2024.
PMID: 37891014
Free PMC article.