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Inhibition of p53-MDM2 binding reduces senescent cell abundance and improves the adaptive responses of skeletal muscle from aged mice.
Nolt GL, Keeble AR, Wen Y, Strong AC, Thomas NT, Valentino TR, Brightwell CR, Murach KA, Patrizia S, Weinstabl H, Gollner A, McCarthy JJ, Fry CS, Franti M, Filareto A, Peterson CA, Dungan CM. Nolt GL, et al. Among authors: filareto a. Geroscience. 2024 Apr;46(2):2153-2176. doi: 10.1007/s11357-023-00976-2. Epub 2023 Oct 24. Geroscience. 2024. PMID: 37872294 Free PMC article.
Deletion of SA β-Gal+ cells using senolytics improves muscle regeneration in old mice.
Dungan CM, Murach KA, Zdunek CJ, Tang ZJ, Nolt GL, Brightwell CR, Hettinger Z, Englund DA, Liu Z, Fry CS, Filareto A, Franti M, Peterson CA. Dungan CM, et al. Among authors: filareto a. Aging Cell. 2022 Jan;21(1):e13528. doi: 10.1111/acel.13528. Epub 2021 Dec 13. Aging Cell. 2022. PMID: 34904366 Free PMC article.
Stem cell therapy for muscular dystrophies.
Biressi S, Filareto A, Rando TA. Biressi S, et al. Among authors: filareto a. J Clin Invest. 2020 Nov 2;130(11):5652-5664. doi: 10.1172/JCI142031. J Clin Invest. 2020. PMID: 32946430 Free PMC article. Review.
Engineered DNA plasmid reduces immunity to dystrophin while improving muscle force in a model of gene therapy of Duchenne dystrophy.
Ho PP, Lahey LJ, Mourkioti F, Kraft PE, Filareto A, Brandt M, Magnusson KEG, Finn EE, Chamberlain JS, Robinson WH, Blau HM, Steinman L. Ho PP, et al. Among authors: filareto a. Proc Natl Acad Sci U S A. 2018 Sep 25;115(39):E9182-E9191. doi: 10.1073/pnas.1808648115. Epub 2018 Sep 4. Proc Natl Acad Sci U S A. 2018. PMID: 30181272 Free PMC article.
22 results