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An allosteric inhibitor of RhoGAP class-IX myosins suppresses the metastatic features of cancer cells.
Kyriazi D, Voth L, Bader A, Ewert W, Gerlach J, Elfrink K, Franz P, Tsap MI, Schirmer B, Damiano-Guercio J, Hartmann FK, Plenge M, Salari A, Schöttelndreier D, Strienke K, Bresch N, Salinas C, Gutzeit HO, Schaumann N, Hussein K, Bähre H, Brüsch I, Claus P, Neumann D, Taft MH, Shcherbata HR, Ngezahayo A, Bähler M, Amiri M, Knölker HJ, Preller M, Tsiavaliaris G. Kyriazi D, et al. Among authors: franz p. Nat Commun. 2024 Nov 16;15(1):9947. doi: 10.1038/s41467-024-54181-6. Nat Commun. 2024. PMID: 39550360 Free PMC article.
Optimizing CAR-T treatment: A T2EVOLVE guide to raw and starting material selection.
Navarro S, Moukheiber C, Inogés Sancho S, Ruiz Guillén M, López-Díaz de Cerio A, Sanges C, Tanaka T, Arnould S, Briones J, Dolstra H, Hudecek M, Choudhary R, Schapitz I, Juan M, Worel N, Ammar D, Luu M, Müller M, Schroeder B, Negre H, Franz P. Navarro S, et al. Among authors: franz p. Mol Ther. 2024 Nov 12:S1525-0016(24)00744-5. doi: 10.1016/j.ymthe.2024.11.017. Online ahead of print. Mol Ther. 2024. PMID: 39533710 Free article. Review.
The spinal muscular atrophy gene product regulates actin dynamics.
Schüning T, Zeug A, Strienke K, Franz P, Tsiavaliaris G, Hensel N, Viero G, Ponimaskin E, Claus P. Schüning T, et al. Among authors: franz p. FASEB J. 2024 Sep 30;38(18):e70055. doi: 10.1096/fj.202300183R. FASEB J. 2024. PMID: 39305126
Single-cell multiomic dissection of response and resistance to chimeric antigen receptor T cells against BCMA in relapsed multiple myeloma.
Rade M, Grieb N, Weiss R, Sia J, Fischer L, Born P, Boldt A, Fricke S, Franz P, Scolnick J, Venkatraman L, Xu S, Kloetzer C, Heyn S, Kubasch AS, Baber R, Wang SY, Bach E, Hoffmann S, Ussmann J, Schetschorke B, Hell S, Schwind S, Metzeler KH, Herling M, Jentzsch M, Franke GN, Sack U, Köhl U, Platzbecker U, Reiche K, Vucinic V, Merz M. Rade M, et al. Among authors: franz p. Nat Cancer. 2024 Sep;5(9):1318-1333. doi: 10.1038/s43018-024-00763-8. Epub 2024 Apr 19. Nat Cancer. 2024. PMID: 38641734
182 results