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Human interleukin-12α and EBI3 are cytokines with anti-inflammatory functions.
Sci Adv. 2023 Oct 27;9(43):eadg6874. doi: 10.1126/sciadv.adg6874. Epub 2023 Oct 25.
Sci Adv. 2023.
PMID: 37878703
Free PMC article.
Assembly-dependent Structure Formation Shapes Human Interleukin-23 versus Interleukin-12 Secretion.
Aschenbrenner I, Siebenmorgen T, Lopez A, Parr M, Ruckgaber P, Kerle A, Rührnößl F, Catici D, Haslbeck M, Frishman D, Sattler M, Zacharias M, Feige MJ.
Aschenbrenner I, et al. Among authors: kerle a.
J Mol Biol. 2023 Dec 1;435(23):168300. doi: 10.1016/j.jmb.2023.168300. Epub 2023 Oct 5.
J Mol Biol. 2023.
PMID: 37805067
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Modeling of the human interleukin 12:receptor complex allows to engineer attenuated cytokine variants.
Liebl K, Aschenbrenner I, Schiller L, Kerle A, Protzer U, Feige MJ.
Liebl K, et al. Among authors: kerle a.
Mol Immunol. 2023 Oct;162:38-44. doi: 10.1016/j.molimm.2023.08.010. Epub 2023 Aug 26.
Mol Immunol. 2023.
PMID: 37639747
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